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Hydrogen is a lightweight, small molecule that is highly flammable and causes an explosion when exposed to air by >4%. It is a colorless and odorless gas; hence, its physical examination is challenging. Therefore, a reliable detection tool is highly demanded to avoid the risk associated with their explosion. Nonetheless, hydrogen sensing is a difficult task that needs a sensitive sensor. Metal nanoparticles (MNPs) and two-dimensional (2D) nanomaterials-based sensors have gained remarkable attention for hydrogen detection. They offer excellent properties such as high active surface area, active sites, porosity, and long-term stability, which make them promising materials for sensor applications. Moreover, a sheet-like structure and flat surface favors a fast adsorption and desorption process. Therefore, the sensing performance of the sensor notably improved. This review deals with the MNPs and 2D nanomaterials such as metal oxides and sulfides, graphene, MXene, metal-organic framework, and polymeric hybrid nanocomposite-based electrochemical and chemiresistive sensors for hydrogen detection. Furthermore, the insight into the mechanistic approaches for hydrogen sensing has been discussed. Lastly, the challenges associated with hydrogen detection, their future advancements, and their commercial perspective have been addressed.
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http://dx.doi.org/10.1002/asia.202500712 | DOI Listing |
Appl Environ Microbiol
September 2025
School of Earth and Space Exploration, Arizona State University, Tempe, Arizona, USA.
Populations of the acidophilic purple nonsulfur bacterium were identified in two geographically distinct thermal areas in Yellowstone National Park (Wyoming, USA), as confirmed by 16S rRNA gene sequencing and detection of characteristic methoxylated ketocarotenoids. Microcosm-based carbon uptake assays where oxygenic photosynthesis was excluded via addition of 3-(3,4-dichlorophenyl)-1,1-dimethylurea yielded a light-driven dissolved inorganic carbon (DIC) assimilation rate (7 ± 2 mg C g C h) comparable to those of highly productive algal mats in acidic hot springs, suggesting that may be performing photoautotrophy at the time of the assay. Rates of acetate assimilation were more than two orders of magnitude lower than DIC assimilation and did not differ between light and dark treatments, indicating photoheterotrophic use of acetate was not occurring, though photoheterotrophic assimilation of other organic compounds cannot be excluded.
View Article and Find Full Text PDFSmall
September 2025
School of Chemistry and Chemical Engineering, Guangxi Key Laboratory of AI-Driven Zero-Carbon Technologies, Key Laboratory of New Low-carbon Green Chemical Technology Education Department of Guangxi Zhuang Autonomous Region, Guangxi University, Nanning, 530004, China.
Sarcosine (Sar), a critical potential biomarker for prostate cancer (PCa), is primarily detected via enzyme cascade reactions involving sarcosine oxidase (SOx) and peroxidase. Nevertheless, the intermediate product hydrogen peroxide (HO) tends to diffuse to the bulk solution phase without entering subsequent reaction, leading to suboptimal detection sensitivity and compromised analytical performance. To tackle this challenge, a multilayered sandwich nanozyme cascade sensor (designated as Cu-MOF/Rf@BDC) is proposed through a confinement-mediated HO enrichment strategy.
View Article and Find Full Text PDFAnal Sens
January 2025
Advanced Imaging Research Center, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390 United States.
At present, two competing hyperpolarization (HP) techniques, dissolution dynamic nuclear polarization (DNP) and parahydrogen (para-H) induced polarization (PHIP), can generate sufficiently high liquid state C signal enhancement for in vivo studies. PHIP utilizes the singlet spin state of para-H to create non-equilibrium spin populations. In hydrogenative PHIP, para-H is irreversibly added to unsaturated precursors, typically in the presence of a homogeneous catalyst.
View Article and Find Full Text PDFChemistry
September 2025
Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, 02129, USA.
Nucleic acid-based therapeutics, such as oncolytic virotherapy or gene therapy, would benefit greatly from a reporter gene that induces endogenous production of a protein biomarker to noninvasively track the delivery, persistence, and spread with imaging. Several chemical exchange saturation transfer (CEST) reporter proteins detectable by magnetic resonance imaging (MRI) have been demonstrated to have high sensitivity. However, to date none can provide strong CEST contrast at a distinct resonance from that of endogenous proteins, limiting their specificity.
View Article and Find Full Text PDFMicrob Cell Fact
September 2025
Biochemistry Division, Chemistry Department, Faculty of Science, Tanta University, Tanta, 31257, Egypt.
Background And Aim: Synthetic dyes in the textile industry pose risks to human health and environmental safety. The current study aims to examine the efficacy of a novel esterase derived from an endophyte fungus in decolorizing diverse dyes, focusing on its production, purification, optimization, and characterization.
Results: Trichoderma afroharzianum AUMC16433, a novel fungal endophyte with esterase-producing ability, was first detected from the cladodes of Opuntia ficus indica by ITS-rRNA sequencing.