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The abrupt dissolution of United States Agency for International Development and the cessation of U.S. President's Emergency Plan for AIDS Relief funding have triggered a global health crisis, disproportionately affecting HIV services and frontline health systems across the Global South. This article explores how nurses are responding-not only by sustaining clinical care but by stepping into roles as policy advocates, organizers, and system innovators. Drawing from lived experiences in Kenya, Malawi, the Philippines, and beyond, we highlight the resilience, leadership, and moral clarity of nurses working through institutional collapse. We argue that nursing is not only a caregiving profession but also a political force essential to rebuilding global health equity. In the face of policy-driven disruption, nurses are advancing solutions grounded in community, advocacy, and cross-border solidarity.
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http://dx.doi.org/10.1097/JNC.0000000000000578 | DOI Listing |
J Biomech
August 2025
Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, USA; Department of Mechanical Engineering & Materials Science, Pratt School of Engineering, Duke University, Durham,
While knee osteoarthritis (OA) is a leading cause of disability in the United States, OA within the patellofemoral joint is understudied compared to the tibiofemoral joint. Mechanical alterations to cartilage may be among the first changes indicative of early OA. MR-based protocols have probed patellar cartilage mechanical function by measuring deformations in response to exercise.
View Article and Find Full Text PDFEur J Radiol
September 2025
Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Rationale/objectives: Image-based vascular biomarkers may help expedite evaluation of chronic thromboembolic pulmonary hypertension (CTEPH), which remains difficult to diagnose despite available effective therapies. We sought to determine if vascular heterogeneity and central redistribution on chest CT differed between CTEPH, pulmonary arterial hypertension (PAH), and control groups.
Materials/methods: We retrospectively included 108 patients who underwent right heart catheterization and chest CT (2011-2018).
Soc Sci Med
September 2025
Indiana University, Department of Sociology, 1020 E. Kirkwood Ave., Bloomington, IN, 47405, USA.
COVID-19 unleashed a bereavement crisis on a scale unseen in over a century. While evidence suggests COVID-19 deaths are acutely damaging to well-being, it is unclear how multiple losses affect mental health, whether there are ethnoracial differences in cumulative loss, or if the association between multiple COVID-related deaths and psychological distress varies by race-ethnicity. Using national survey data (n = 1810) collected following the Omicron surge in the United States, we estimate a series of regression models to assess the association between multiple COVID-19 losses and psychological distress, racial-ethnic differences in aggregate death exposure, and differential vulnerability to multiple losses across racial-ethnic groups.
View Article and Find Full Text PDFBiochemistry
September 2025
Loyola University Chicago, Department of Chemistry and Biochemistry, 1068 W Sheridan Rd, Chicago, Illinois 60660, United States.
Dihydroorotate dehydrogenase 1B (DHOD1B) is one of several flavoproteins that utilize active half-sites. These enzymes have two flavin cofactors (FAD and FMN) that each interact with a specific reductant/oxidant substrate/product. Electrons gained at one-half-site must be transmitted to the other half-site and iron-sulfur centers between the flavin cofactors serve in this role.
View Article and Find Full Text PDFBrief Bioinform
September 2025
Department of Computer Science, Hanyang University, 222 Wangsimni-ro, Seoul 04763, Republic of Korea.
Motivation: Mobile genetic elements (MGEs) play an important role in facilitating the acquisition of antibiotic resistance genes (ARGs) within microbial communities, significantly impacting the evolution of antibiotic resistance. Understanding the mechanism and trajectory of ARG acquisition requires a comprehensive analysis of the ARG-carrying mobilome-a collective set of MGEs carrying ARGs. However, identifying the mobilome within complex microbiomes poses considerable challenges.
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