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Optical scanning holography (OSH) emerges as a groundbreaking single-pixel real-time holographic recording technique, charting new territory beyond conventional digital holography. A notable challenge in OSH, as with all three-dimensional (3D) imaging methods, is the susceptibility of reconstructed images corrupted by defocus noise. The noise is an unintended result of diffraction on the focused plane from out-of-focus planes of the three-dimensional object, which can degrade image quality upon holographic reconstruction. Current methods, however, all use some algorithms to post-process holographic data to achieve the purpose of eliminating out-of-focus noise, which is difficult to meet the requirements of real-time image processing. We propose an innovative pre-processing approach in optical scanning holography that not only eliminates defocus noise but also significantly enhances image quality. Preprocessing is accomplished by the utilization of a focus-tunable lens (FTL) to refocus the optical scanning beam according to the depth of the occlusion-free object. Complex holograms are then captured without the artifacts associated with defocus through real-time holographic data pre-processing. Numerical simulations and experimental results demonstrate that our proposed method can directly obtain high-quality reconstructed images with all the 3D information being in focus simultaneously.
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http://dx.doi.org/10.1364/OE.545339 | DOI Listing |
Light Sci Appl
September 2025
Laboratory of Quantum Information, University of Science and Technology of China, 230026, Hefei, China.
Quantum imaging with spatially entangled photons offers advantages such as enhanced spatial resolution, robustness against noise, and counterintuitive phenomena, while a biphoton spatial aberration generally degrades its performance. Biphoton aberration correction has been achieved by using classical beams to detect the aberration source or scanning the correction phase on biphotons if the source is unreachable. Here, a new method named position-correlated biphoton Shack-Hartmann wavefront sensing is introduced, where the phase pattern added on photon pairs with a strong position correlation is reconstructed from their position centroid distribution at the back focal plane of a microlens array.
View Article and Find Full Text PDFAJNR Am J Neuroradiol
September 2025
From the Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America (J.S.S., B.M., S.H., A.H., J.S.), and Department of Aerospace Engineering, Indian Institute of Technology Madras, Chennai, Tamil Nadu, India (H.S.).
Background And Purpose: The choroid of the eye is a rare site for metastatic tumor spread, and as small lesions on the periphery of brain MRI studies, these choroidal metastases are often missed. To improve their detection, we aimed to use artificial intelligence to distinguish between brain MRI scans containing normal orbits and choroidal metastases.
Materials And Methods: We present a novel hierarchical deep learning framework for sequential cropping and classification on brain MRI images to detect choroidal metastases.
Talanta
September 2025
Universidad Autónoma de Madrid, Avda. Francisco Tomás y Valiente, 7, Madrid, 28049, Spain.
Gold nanoparticles (Au NPs) are widely used in diverse technological and scientific applications due to their unique optical and catalytic properties. These properties are strongly influenced by the size, shape, composition, and/or concentration of the NPs, which in turn depend on the synthesis conditions. Therefore, the development of simple, cost-effective, and reliable analytical methods for their characterization is essential.
View Article and Find Full Text PDFCryobiology
September 2025
Faculty of Agriculture and Life Science, Hirosaki University, 3 Bunkyo-cho, Hirosaki, Aomori, 036-8561, Japan. Electronic address:
The concentration dependence of ice-crystal formation during cooling and rewarming of sucrose solutions (51-72 wt%) was studied by differential scanning calorimetry and optical microscopy at cooling and heating rates of ±1.0-±3.0 °C/min.
View Article and Find Full Text PDFRetina
September 2025
Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, CH-3010.
Purpose: To evaluate inter-grader variability in posterior vitreous detachment (PVD) classification in patients with epiretinal membrane (ERM) and macular hole (MH) on spectral-domain optical coherence tomography (SD-OCT) and identify challenges in defining a reliable ground truth for artificial intelligence (AI)-based tools.
Methods: A total of 437 horizontal SD-OCT B-scans were retrospectively selected and independently annotated by six experienced ophthalmologists adopting four categories: 'full PVD', 'partial PVD', 'no PVD', and 'ungradable'. Inter-grader agreement was assessed using pairwise Cohen's kappa scores.