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Online aggression is a serious social problem in the Internet era, which seriously threatens the physical and mental health of individuals. Exploring how online aggression differs from offline aggression can help us develop targeted prevention and intervention measures. However, the basic difference between online aggression and traditional offline aggression remains unclear. This study tried to address the issues from the perspective of structure and predictors by using network analysis in 1,009 Chinese college students. The dimensions of online and traditional offline aggression were utilized to detect the community. And incorporate individual and situational predictors as nodes for network analysis. The results showed that the nodes of Cyber-Aggression Typology Questionnaire and Buss Perry Aggression Questionnaire were divided into two distinct communities. The edge-weight bootstrapped difference test showed that callous-unemotional traits, trait anger, empathy, and guilt were only associated with offline aggression. Furthermore, moral disengagement and social exclusion were more closely associated with offline aggression than online aggression, while violent attitude was more associated with online aggression. These findings support and expand the Barlett and Gentile Cyberbullying Model, enhancing our comprehension of both offline and online aggression, and providing inspiration for prevention and intervention in offline and online aggression in the future.
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http://dx.doi.org/10.1177/21522715251360547 | DOI Listing |
Oncogene
September 2025
Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Pancreatic cancer is a highly aggressive malignancy with a dismal prognosis, characterized by a complex tumor microenvironment that promotes immunosuppression and limits the efficacy of immune checkpoint blockade (ICB) therapy. Fibroblast activation protein (FAP) is overexpressed in the tumor stroma and represents a promising target for therapeutic intervention. Here, we developed a novel antibody-drug conjugate (ADC) targeting FAP, and investigated its anti-tumor activity and ability to enhance ICB efficacy in pancreatic cancer.
View Article and Find Full Text PDFJ Am Vet Med Assoc
September 2025
4Animal Behavior Clinic, John and Ann Tickle Small Animal Hospital, College of Veterinary Medicine, University of Tennessee, Knoxville, TN.
Objective: The purpose of our study was to investigate the relationship between patient handling techniques and the incidence of patient-inflicted injury to veterinary staff. Furthermore, we aimed to characterize hospitals' postinjury care protocols.
Methods: This cross-sectional study was conducted on convenience sample data of small animal general practices in the US and Canada, collected via an online survey.
Int Emerg Nurs
September 2025
Professor, School of Health & Biomedical Sciences, Royal Melbourne Institute of Technology (RMIT) University, Melbourne, Australia. Electronic address:
Background: ST-segment elevation myocardial infarction (STEMI) demands aggressive and rapid medical intervention. Delays in Door-to-balloon time (DTB) of more than 90 min cause progressive damage to the cardiac tissue and require immediate medical intervention, including percutaneous coronary intervention (PCI). Nurses and doctors in STEMI management face several challenges that result in a delay in DTB time.
View Article and Find Full Text PDFJAACAP Open
September 2025
University of Miami, Coral Gables, Florida.
Objective: Researchers have differentiated forms (overt, relational) and functions (proactive, reactive) of aggressive behavior; however, the assessment options for measuring these constructs in youth remain limited. This study examined the parent-report Peer Conflict Scale (PCS) for measuring forms and functions of youth aggressive behavior in English and Spanish, including short- and long-form versions.
Method: Participants were caregivers of 653 youths (ages 6-17; 57% male; 48% Hispanic) throughout North America.
JMIR Infodemiology
September 2025
Center for Enhancing Quality of Life in Chronic Illness, School of Nursing, Indiana University Indianapolis, 600 Barnhill Drive, Indianapolis, IN, 46202, United States, 1 574-703-4472.
Background: Cyber victimization exposes individuals to numerous risks. Developmental and psychological factors may leave some users unaware of the potential dangers, increasing their susceptibility to psychological distress. Despite this vulnerability, methods for identifying those at risk of cyber victimization within health care settings are limited, as is research that explores their experiences of cyber victimization.
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