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This study developed and validated a Python-based program for analyzing the region of interest mean values using red-green-blue (RGB)-reconstructed perfusion-weighted imaging (PWI) data. The program addressed the limitations of traditional source-image-based analysis, including manufacturer dependency, high storage costs, and limited accessibility. High intraclass correlation coefficient (ICC) values for cerebral blood volume and time to peak confirmed the feasibility of this approach, whereas lower ICC values for mean transit time suggested discrepancies between reconstructed RGB images and conventional dynamic susceptibility contrast-based data. Designed with a user-friendly graphical user interface and executable distribution, the program enhances clinical applicability. Future studies should focus on improving the algorithms and validating the approach with multicenter datasets.
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http://dx.doi.org/10.3233/SHTI250969 | DOI Listing |
Can Assoc Radiol J
July 2025
Department of Diagnostic Imaging, Division of Neuroradiology, University of Toronto, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.
Purpose: Accurate vessel measurement is essential in endovascular thrombectomy (EVT) for acute ischemic stroke. Discrepancies between computed tomography angiography (CTA) and digital subtraction angiography (DSA) may impact procedural planning and device selection. This study compares vessel diameter measurements from CTA and DSA in patients with middle cerebral artery (MCA) M1 occlusions.
View Article and Find Full Text PDFWound Repair Regen
September 2025
Graduate Program in Health Technology (PPGTS) at Pontifical Catholic University of Paraná (PUC-PR), Paraná, Brazil.
Chronic wounds pose a growing global health challenge. Accurate assessment is essential for monitoring healing, yet traditional two-dimensional methods lack volumetric analysis. Emerging three-dimensional imaging technologies offer enhanced precision, but their clinical validation and prognostic utility remain unclear.
View Article and Find Full Text PDFAm J Hum Biol
September 2025
University of California, San Francisco, San Francisco, California, USA.
Background: Telomere length (TL) is a valuable marker of aging and stress that reflects both genetic and environmental influences. Quantitative PCR (qPCR) TL measurement is a powerful and cost-effective assay, especially in population studies with limited quantities of source material. Nevertheless, collecting and transporting high-quality blood samples can be logistically challenging, and research suggests that several preanalytical and analytical factors can influence the reliability and precision of the qPCR assay.
View Article and Find Full Text PDFWorld Neurosurg
September 2025
Department of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing, China. Electronic address:
Background: Frontal patient state index (PSI) monitoring is impractical during frontal lobe tumor resection due to surgical field interference. No validated alternative monitoring positions exist currently. This study evaluated the agreement between standard frontal and experimental occipital PSI monitoring.
View Article and Find Full Text PDFSleep Breath
September 2025
Université Paris Cité, NeuroDiderot, Inserm U1141, Paris, F-75019, France.
Purpose: obstructive sleep apnea is underdiagnosed due to limited access to polysomnography (PSG). We aimed to assess the performances of Apneal, an application recording sound and movements thanks to a smartphone's microphone, accelerometer and gyroscope, to estimate patients' apnea-hypopnea index (AHI).
Methods: monocentric proof-of-concept study with a first manual scoring step, then automatic detection of respiratory events from recorded signals using a sequential deep-learning model (version 0.