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This study explores how artificial intelligence technologies can enhance the regulatory capacity for legal risks in internet healthcare based on a machine learning (ML) analytical framework and utilizes data from the health insurance portability and accountability act (HIPAA) database. The research methods include data collection and processing, construction and optimization of ML models, and the application of a risk assessment framework. Firstly, the data are sourced from the HIPAA database, encompassing various data types, such as medical records, patient personal information, and treatment costs. Secondly, to address missing values and noise in the data, preprocessing methods such as denoising, normalization, and feature extraction are employed to ensure data quality and model accuracy. Finally, in the selection of ML models, this study experiments with several common algorithms, including extreme gradient boosting (XGBoost), support vector machine (SVM), random forest (RF), and deep neural network (DNN). Each algorithm has its strengths and limitations depending on the specific legal risk assessment task. RF enhances classification performance by integrating multiple decision trees, while SVM achieves efficient classification by identifying the maximum margin hyperplane. DNN demonstrates strong capabilities in handling complex nonlinear relationships, and XGBoost further improves classification accuracy by optimizing decision tree models through gradient boosting. Model performance is evaluated using metrics such as accuracy, recall, precision, F1 score, and area under curve (AUC) value. The experimental results indicate that the DNN model performs excellently in terms of F1 score, accuracy, and recall, showcasing its efficiency and stability in legal risk assessment. The principal component analysis-random forest (PCA+RF) and RF models also exhibit stable performance, making them suitable for various application scenarios. In contrast, the SVM and K-Nearest Neighbor models perform relatively weaker, although they still retain some validity in certain contexts, their overall performance is inferior to deep learning and ensemble learning methods. This study not only provides effective ML tools for legal risk assessment in internet healthcare but also offers theoretical support and practical guidance for future research in this field.
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http://dx.doi.org/10.1038/s41598-025-13720-x | DOI Listing |
J Med Screen
September 2025
Institute of Cardiovascular Science, University College London, London, UK.
It is claimed that polygenic risk scores will transform disease prevention, but a typical polygenic risk score for a common disease only detects 11% of affected individuals at a 5% false positive rate. This level of screening performance is not useful. Claims to the contrary are either due to incorrect interpretation of the data or other influences.
View Article and Find Full Text PDFInt J Surg
September 2025
Department of Oral and Maxillofacial Surgery, The Affiliated Tai'an City Central Hospital of Qingdao University, Taian, China.
Int J Surg
September 2025
Department of Pharmacy, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, School of Clinical Medicine, Henan University, Zhengzhou, Henan, China.
Background: Antiplatelet therapy is a cornerstone in the management of atherosclerotic cardiovascular disease. However, the risk profile of central nervous system (CNS) hematomas associated with antiplatelet agents remains incompletely characterized.
Methods: We analyzed CNS-related hematoma adverse event (hAE) reports across the four antiplatelet drugs, using data from the U.
J Urban Health
September 2025
School of Architecture and Design, Harbin Institute of Technology, Harbin, 150001, China.
Street-level environments play a vital role in children's development by promoting their physical activity, cognitive growth, and overall development. This study systematically reviews the measurement tools available to assess street environments according to children's needs. This systematic review was conducted according to the PRISMA-COSMIN guidelines.
View Article and Find Full Text PDFInfect Dis Ther
September 2025
Department of Nursing, Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, China.
Introduction: Cognitive frailty (CF), which typically precedes dementia and functional decline, serves as a more robust predictor of adverse health outcomes compared to physical frailty alone, representing a critical challenge in promoting healthy aging among older people living with HIV (PLWH) aged ≥ 50 years. This study aimed to investigate the prevalence of cognitive frailty and identify its associated factors among PLWH aged ≥ 50 years.
Methods: A convenience sample of 344 PLWH ≥ 50 years was recruited from a tertiary Grade A hospital in Zunyi, China.