Creatine Supplementation for Cognition: A Critical Perspective on Promise, Proof, and Public Perception.

J Nutr

Independent researcher, Porto Alegre, Rio Grande do Sul, Brazil. Electronic address:

Published: July 2025


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Article Abstract

Creatine is widely regarded as a safe and effective supplement for physical performance but has recently gained attention as a potential cognitive enhancer. Public and commercial enthusiasm for this use has surged, spiking sales, prescriptions and social media engagement despite a body of evidence that, paradoxically, haved remained considerably limited. This article critically examines the growing disconnect between marketing narratives and scientific rigor in the discourse around creatine and brain health. It also explores how biases, both cognitive and structural, shapes how the evidence is interpreted and communicated. Rather than dismissing creatine's potential, the essay argues for greater critical appraisal and transparency in how health claims are evaluated and disseminated, to ensure that conversations remain anchored to what the data can actually support.

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http://dx.doi.org/10.1016/j.tjnut.2025.07.016DOI Listing

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