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The ∼60 000 solar-mass (M_{⊙}) star cluster R136 (NGC 2070) in the Tarantula Nebula in the Large Magellanic Cloud is the host of at least 55 massive stars (M≳10M_{⊙}) which move away from the cluster at projected velocities ≥27.5 km/s. The origin of the high velocities of such runaway stars have been debated since the 1960s, resulting either from dynamical ejections or from supernova explosions. Because of the Gaia satellite's outstanding precision, we can now retrace the most recently ejected binary star, Mel 34, back to the center of R136 and reconstruct the events that 52 000 years ago led to its removal from R136; i.e., we establish its dynamical interaction and ejection history. We find that this ejection requires the participation of five stars in a strong interaction between a triple composed of the tight massive binary Mel 39, orbited by the star VFTS 590, and the binary star Mel 34. The participation of five stars is unexpected because runaway stars were not expected to result from triple interactions. The deterministic nature of the Newtonian dynamics in the scattering enables us to reconstruct the encounter that ejected Mel 34. We then predict that Mel 39 is a binary star with an 80M_{⊙} companion star that orbits within ∼1° in the same plane as Mel 34 and escapes the cluster with a velocity of ∼64 km/s. The five stars will undergo supernova explosions in the coming 5 Myr at a distance of ∼180-332 pc from their birth location (R136). The resulting black hole binaries, however, are not expected to merge within a Hubble time.
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http://dx.doi.org/10.1103/n43y-wt19 | DOI Listing |
Inorg Chem
September 2025
The Key Laboratory of the Materials for Energy Conversion and Storage of Shanxi Province, Institute of Molecular Science, Shanxi University, 92 Wucheng Road, Taiyuan, Shanxi 030006, People's Republic of China.
For over half a century, clusters exhibiting unconventional bonding have captivated researchers due to their unique electronic characteristics. While most elements in the periodic table demonstrate this remarkable structural feature, sulfur has been notably absent from known global minima with a planar pentacoordinate center. Herein, we report the first binary dianion cluster, SMg, featuring a planar pentacoordinate sulfur (ppS) atom.
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September 2025
Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen 9700 RB, the Netherlands. Electronic address:
Research on multimorbidity patterns promotes our understanding of the common pathological mechanisms that underlie co-occurring diseases. Here, we present a protocol to infer multimorbidity clusters in the form of disease topics from large-scale diagnosis data using treeLFA, a topic model based on the Bayesian binary non-negative matrix factorization. We describe steps for installing software, preparing input data, and training the model.
View Article and Find Full Text PDFScience
September 2025
LIGO Laboratory, California Institute of Technology, Pasadena, CA, USA.
Improved low-frequency sensitivity of gravitational wave observatories would unlock study of intermediate-mass black hole mergers and binary black hole eccentricity and provide early warnings for multimessenger observations of binary neutron star mergers. Today's mirror stabilization control injects harmful noise, constituting a major obstacle to sensitivity improvements. We eliminated this noise through Deep Loop Shaping, a reinforcement learning method using frequency domain rewards.
View Article and Find Full Text PDFNat Commun
September 2025
John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, 02138, USA.
The surge in artificial intelligence applications calls for scalable, high-speed, and low-energy computation methods. Computing with photons is promising due to the intrinsic parallelism, high bandwidth, and low latency of photons. However, current photonic computing architectures are limited by the speed and energy consumption associated with electronic-to-optical data transfer, i.
View Article and Find Full Text PDFJ Cheminform
August 2025
Bioinformatics Institute, Agency for Science, Technology and Research, 30 Biopilis Street, Singapore, 138671, Singapore.
Cyclic peptides are promising drug candidates due to their ability to modulate intracellular protein-protein interactions, a property often inaccessible to small molecules. However, their typically poor membrane permeability limits therapeutic applicability. Accurate computational prediction of permeability can accelerate the identification of cell-permeable candidates, reducing reliance on time-consuming and costly experimental screening.
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