Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297366 | PMC |
| http://dx.doi.org/10.1038/s41420-025-02562-1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Refining Structural Analysis of Proteins: Automated Methods to Measure Transition Dipole Strength of Single Residues.
J Phys Chem B
August 2025
Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
Transition dipole strength (TDS) analysis enhances two-dimensional infrared (2D IR) spectroscopy by probing protein structural differences that frequency alone cannot resolve. However, its application has been limited to strong signals due to challenges with low signal-to-noise and large backgrounds in the linear optical density. Manual baseline correction can suffer from user error and produce large artifacts that obscure signals of interest.
View Article and Find Full Text PDFCorrection to: IAPP modulates cellular autophagy, apoptosis, and extracellular matrix metabolism in human intervertebral disc cells.
Cell Death Discov
July 2025
Department of Orthopaedic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Author Correction: Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc.
Exp Mol Med
June 2025
Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Cagrilintide is not associated with clinically relevant QTc prolongation: A thorough QT study in healthy participants.
Diabetes Obes Metab
December 2024
Novo Nordisk A/S, Søborg, Denmark.
Aims: The combination of cagrilintide and semaglutide (CagriSema) is being developed for the treatment of obesity and type 2 diabetes. The objective of this thorough QT study was to confirm that cagrilintide does not result in a clinically relevant prolongation in cardiac repolarization compared with placebo.
Materials And Methods: This was a double-blind study (NCT05804162) in which healthy participants were randomized to cagrilintide, administered as a once-weekly subcutaneous injection dose escalated to 4.
Okinawa-Based Nordic Diet Decreases Plasma Glial Fibrillary Acidic Protein Levels in Type 2 Diabetes Patients.
Nutrients
August 2024
Department of Internal Medicine, Lund University, Skåne University Hospital, 214 28 Malmö, Sweden.
Elevated levels of glial fibrillary acidic protein (GFAP) in plasma reflect neuroinflammation and are linked to cognitive decline. Preclinical studies show that dietary change can attenuate astrocyte reactivity and neuroinflammation. In the current study, we investigate if the Okinawa-based Nordic (O-BN) diet alters plasma GFAP levels in patients with Type 2 Diabetes (T2D), a metabolic disorder associated with cognitive disturbances and an increased risk of dementia.
View Article and Find Full Text PDF