Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
An efficient palladium-catalyzed C-H silylation of 1-(2-iodophenyl)-1-indoles has been developed. The reaction exhibits an obvious electronic effect. This protocol uses Pd(OAc) as a catalyst with hexamethyldisilane as the trimethylsilyl source. The reaction exhibits good functional group tolerance and provides straightforward access to diverse silicon-containing indoles under relatively mild conditions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.joc.5c00863 | DOI Listing |
Publication Analysis
Top Keywords
silylation 1-2-iodophenyl-1-indoles
8
reaction exhibits
8
palladium-catalyzed silylation
4
1-2-iodophenyl-1-indoles intramolecular
4
intramolecular c-h
4
c-h activation
4
activation efficient
4
efficient palladium-catalyzed
4
palladium-catalyzed c-h
4
c-h silylation
4