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Community health outcomes significantly impact older populations' wellbeing and quality of life. Traditional analytical methods often struggle to accurately predict health risks at the community level due to their inability to capture complex, non-linear relationships among various health determinants. This study employs a Random Forest Algorithm (RFA) to address this limitation and enhance the predictive modeling of community health outcomes. By leveraging ensemble learning techniques and multi-factor analysis, this study aims to identify and quantify the relative contributions of key health indicators to risk assessment. The study begins with comprehensive data collection from diverse health sources, followed by a systematic preprocessing stage, which includes resolving missing values, normalizing variables, and encoding categorical features. Using bootstrap sampling, multiple decision trees were trained on random subsets of health data, ensuring variability in the model learning. The trees grow to full depth and aggregate their predictions to enhance the accuracy. An out-of-bag (OOB) error estimation was applied to refine the model and provide unbiased performance assessments, ensuring robust generalization to unseen data. The proposed model effectively analyzes key health indicators, ranking the feature importance to determine the most influential predictors of health risks. Results indicate that RFA achieves an accuracy rate of 92%, outperforming conventional prediction methods in terms of precision and recall. These findings underscore the efficacy of Random Forest in identifying critical health risk factors, paving the way for targeted and data-driven public health management strategies and interventions tailored to older adults.
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http://dx.doi.org/10.3389/fdata.2025.1574683 | DOI Listing |
Genet Med
September 2025
Institute for Clinical and Translational Science, University of California, Irvine, CA, USA.
Purpose: Advancements in sequencing technologies have significantly improved clinical genetic testing, yet the diagnostic yield remains around 30-40%. Emerging technologies are now being deployed to address the remaining diagnostic gap.
Methods: We tested whether short-read genome sequencing could increase the diagnostic yield in individuals enrolled into the UCI-GREGoR research study, who had suspected Mendelian conditions and prior inconclusive testing.
J Sci Food Agric
September 2025
Department of Nutrition and Dietetics, Hamidiye Faculty of Health Sciences, University of Health Sciences, Istanbul, Türkiye.
Background: This study aimed to develop gluten-free bread from chickpea flour by incorporation of varying levels (0 (B-C), 2.5 (B-1), 5 (B-2), and 10 g kg (B-3)) of madımak leaf powder (MLP), and to investigate its effect on physicochemical and bioactive properties, glycemic index, texture, and sensory attributes.
Results: Moisture ranged from 229 (B-3) to 244 g kg (control), while ash content increased with MLP, reaching 47 g kg in B-3 compared to 15.
Scand J Med Sci Sports
September 2025
Department of Dermatology and Allergy Biederstein, School of Medicine and Health, TUM University Hospital Rechts der Isar, Munich, Germany.
In wheat allergy dependent on augmentation factors (WALDA), allergic reactions occur when wheat ingestion is combined with exercise or rarely other augmentation factors. We analyzed clinical characteristics and disease burden in recreationally active and trained individuals with WALDA diagnosed by oral challenge test. Clinical characteristics, serological data, and quality of life (QOL) questionnaires were analyzed and completed with follow-up interviews.
View Article and Find Full Text PDFAnal Methods
September 2025
Key Laboratory of Biorheological Science and Technology of Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, P. R. China.
Aflatoxin B1 (AFB1) is one of the most toxic mycotoxins that pose great health threats to humans. Herein, an aptasensor-based fluorescent signal amplification strategy is developed for the detection of AFB1. Initially, the AFB1 aptamers labelled with carboxyfluorescein (FAM) are adsorbed onto graphene oxide (GO), triggering energy transfer.
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