An effective dual functional indole-based probe for sensing Ni and Ce ions respectively.

Spectrochim Acta A Mol Biomol Spectrosc

College of Chemistry and Chemical Engineering, Xinjiang Normal University, Urumqi 830054, China. Electronic address:

Published: January 2026


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

A novel indole-based acylhydrazone derivative has been synthesized and characterized by the four spectrums (H and C NMR, IR, and HRMS). The configuration of acylhydrazone is confirmed to be EE through X-ray diffraction. This probe demonstrates a bifunctional chemosensor for the detection of Ni and Ce via distinct optical responses, which exhibits an AIE fluorescence on response to Ce, LOD = 4.24 × 10 M, and a fluorescence off response for Ni, LOD = 3.15 × 10 M. Job's plot analysis confirms the formation of a 1:1 stoichiometric complex between the probe and Ni. Furthermore, the probe IPCA also demonstrates as a triple-mode sensor to Ni, enabling naked-eye colorimetric detection under natural light.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.saa.2025.126703DOI Listing

Publication Analysis

Top Keywords

fluorescence response
8
effective dual
4
dual functional
4
functional indole-based
4
probe
4
indole-based probe
4
probe sensing
4
sensing ions
4
ions novel
4
novel indole-based
4

Similar Publications

Development of smartphone-based AIE fluorescence-quenching immunochromatographic sensors for the detection of illicit drugs in various complex sample matrices.

Anal Bioanal Chem

September 2025

GuangDong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.

Illicit drug abuse poses a significant global threat to public health and social security, highlighting the urgent need for rapid, sensitive, and versatile detection technologies. To address the limitations of traditional chromatographic techniques-such as high costs and slow response times-and the drawbacks of conventional immunochromatographic sensors (ICS), including low sensitivity and non-intuitive signal outputs, a fluorescence-quenching ICS (FQICS) was developed. This sensor leverages fluorescence resonance energy transfer (FRET) between aggregation-induced emission fluorescent microspheres (AIEFMs) and gold nanoparticles (AuNPs).

View Article and Find Full Text PDF

A triphenyl-imidazole end-capped donor-acceptor type potential molecular probe 3 has been designed and synthesized. Probe 3 upon interaction with different classes of metal ions/anions and NPPs displayed high selectivity with CN anion (LOD = 20.42 nM) through fluorescence "turn-Off" response and a naked-eye sensitive visible color change.

View Article and Find Full Text PDF

Photothermal/GSH-dual-responsive organic quantum dots enabling traceable DNA delivery.

Int J Biol Macromol

September 2025

School of Life Science and Technology, Wuhan Polytechnic University, Wuhan, 430023, China. Electronic address:

Quantum dots, with their superior intrinsic fluorescence and photostability, are emerging as a promising option for cancer gene therapy, diagnosis, and imaging. However, low gene delivery efficiency, insufficient targeting, and responsiveness remain challenges. To address these issues, PEI-based carbon quantum dots (CPNCs) were constructed by crosslinking polyethylenimine quantum dots (PQDs) with carbon quantum dots (CQDs) via disulfide bonds.

View Article and Find Full Text PDF

In response to the new operational quantities proposed in ICRU Report 95, we calculated conversion coefficients for monoenergetic photon calibration fields-specifically, theAm γ-ray calibration field and the fluorescence X-ray calibration field-both of which are listed in the annex of the ISO 4037 standard series. These coefficients were derived using measured photon spectral fluence. Additionally, correction factors for air density were determined for the low-energy fluorescence X-ray calibration field.

View Article and Find Full Text PDF

A new water soluble mitochondria targeted ESIPT active acylhydrazone for the specific detection of Zn and S ions and bioimaging in HeLa cells.

Spectrochim Acta A Mol Biomol Spectrosc

September 2025

Laboratorio de Química Inorgánica y Organometálica, Departamento de Química Analítica e Inorgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Edmundo Larenas 129, Casilla 160-C, Concepción, Chile. Electronic address:

The development of multifunctional fluorescent organic materials capable of selective ion detection, subcellular targeting, and logical operations is a burgeoning area in chemical biology and materials science. Herein, we report the design and development of a novel acylhydrazone based fluorescent ligand (HSN·Cl), which exhibits a distinct "turn-on" emission response toward Zn ions and a subsequent "turn-off" response in the presence of sulfide ions (S). The molecular design incorporates structural elements that facilitate the ESIPT feature, conferring the probe with unique photophysical properties.

View Article and Find Full Text PDF