A new water soluble mitochondria targeted ESIPT active acylhydrazone for the specific detection of Zn and S ions and bioimaging in HeLa cells.

The development of multifunctional fluorescent organic materials capable of selective ion detection, subcellular targeting, and logical operations is a burgeoning area in chemical biology and materials science. Herein, we report the design and development of a novel acylhydrazone based fluorescent ligand (HSN·Cl), which exhibits a distinct "turn-on" emission response toward Zn ions and a subsequent "turn-off" response in the presence of sulfide ions (S). The molecular design incorporates structural elements that facilitate the ESIPT feature, conferring the probe with unique photophysical properties.

An interesting aggregation induced red shifted emissive and ESIPT active hydroxycoumarin tagged symmetrical azine: Colorimetric and fluorescent turn on-off-on response towards Cu and Cysteine, real sample analysis and logic gate application.

We report a newly synthesized 7-diethylamino-4-hydroxycoumarin tagged symmetrical azine derivative (SHC), with an interesting color transformation from yellowish green to orange via aggregation induced red shifted emissive (117 nm) feature in THF-HO mixture. Interestingly, the single crystal X-ray analysis of this molecule demonstrates that two hydroxycoumarin moieties were present in azine unit, among them one of the coumarin units was exist as enol form and another one transferred to keto form via ground state proton transfer reaction. The optical responses of the compound in different solvents exposed the observation of dual emissive bands which corresponds to the presence of ESIPT phenomenon in SHC molecule.

3-Ethoxysalicylaldimine-based symmetrical azine-linked luminogen exhibiting ESIPT and bright orange colour AIE behaviour with live cell bioimaging application.

Herein, we describe the design and development of a new cell-permeable aggregation-induced emission (AIE) active 3-ethoxysalicylaldimine-based symmetrical azine molecule HDBE. The synthesized compound underwent comprehensive investigation of different spectroscopic methods, like NMR, mass and single crystal X-ray diffraction analysis. The fluorophore HDBE exhibited the bright orange colour AIE behaviour in THF-HO mixture.

C-symmetric triaminoguanidine based colorimetric and fluorometric chemosensor: Sequential detection of Zn/PPi, its RGB performance for detection of Zn ion and construction of IMPLICATION logic gate.

In this work, new ethyl(E)-2-cyano-3-(1H-pyrrol-2-yl)acrylate appended C-symmetric star-shape triaminoguanidine based Schiff base (LH) was designed and synthesized from simple synthons. New probe, LH was completely analyzed by H NMR, C NMR and mass spectrum. In the present probe LH, effective π-conjugated ethyl(E)-2-cyano-acrylate unit was introduced on the periphery of the pyrrole-triaminoquanidine conjugates by using carefully chosen building units.

Simple C-symmetric triaminoguanidine-triphenylamine conjugate as an efficient colorimetric sensor for Cu(II) and fluorescent sensor for Fe(III) ions.

The design and construction of novel C-symmetric triaminoguanidine-triphenylamine conjugate (L) has been demonstrated and it displays positive solvatochromic behaviour with an increase in solvent polarity. The probe L acts as a selective colorimetric sensor for Cu ions over other metal ions. Further, it shows high selective and sensitive detection of Fe ions through turn-on fluorescence response.

Selective detection of pyrophosphate anion by zinc ensemble of C-symmetric triaminoguanidine-pyrrole conjugate and its biosensing applications.

A new-fangled C-symmetric triaminoguanidine-pyrrole conjugate has been constructed and utilized for sensing applications. The probe selectively detects zinc ions (Zn) by colorimetric as well as turn-on fluorescent manner. Further, the in-situ formed zinc ensemble displays turn-off fluorescence response towards the pyrophosphate anion (PPi) via displacement approach.

Star-Shaped ESIPT-Active Mechanoresponsive Luminescent AIEgen and Its On-Off-On Emissive Response to Cu/S.

Design and development of multifunctional materials have drawn incredible attraction in recent years. Herein, we report the design and construction of versatile star-shaped intramolecular charge transfer (ICT)-coupled excited-state intramolecular proton transfer (ESIPT)-active mechanoresponsive and aggregation-induced emissive (AIE) luminogen triaminoguanidine-diethylaminophenol ( ) conjugate from simple precursors triaminoguanidine hydrochloride and 4-(,-diethylamino)salicylaldehyde. Solvent-dependent dual emission in nonpolar to polar protic solvents implies the presence of ICT-coupled ESIPT features in the excited state.