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Article Abstract
Herein, we report a straightforward synthetic protocol to afford a series of novel Uracil-based bench-stable cyclic hypervalent iodine reagents, Uracil-benziodoxolone ( Uracil-BX). The 3c-4e weak bonds of these hitherto unreported hypervalent iodine reagents were also synthetically exploited for sulfenylation and amination at the C5 position of Uracil via an umpolung strategy. Metal-free approaches for this functionalization at the C5 position lead to various interesting Uracil derivatives that resemble medicinally important molecules.
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