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Aim: Sustainability of dental polymethyl methacrylate (PMMA) in acidic environments is crucial as oral pH fluctuations can degrade the mechanical properties of denture bases. PMMA strengthening with polypropylene (PP) mesh has improved mechanical properties, but its effectiveness in acidic conditions remains underexplored. This investigation aimed to evaluate the mechanical properties of PP mesh reinforced PMMA (PP-PMMA) on exposure to an acidic environment as against unreinforced denture base resin (UN-PMMA).
Settings And Design: Experimental In-vitro study.
Materials And Methods: A total of 120 PMMA samples were prepared as per standardized guidelines and divided into two groups as unreinforced and PP - PMMA. Prepared specimens were immersed in artificial saliva and simulated gastric acid (0.06M HCl, pH 1.2) at 37°C for 96 hours to simulate long-term clinical exposure to an acidic environment. Flexural strength, impact strength, surface roughness and microscopic characteristics were assessed with aid of universal testing machine, Izod's impact tester, profilometer and high-resolution scanning electron microscope (HR-SEM) in order.
Statistical Analysis Used: The data were statistically analyzed using ANOVA and independent t-test set at a significance level of P-values less than 0.05.
Results: PP-PMMA exhibited significantly higher flexural strength in simulated gastric acid (70.03±1.4MPa) compared to UN-PMMA (68.77±2.2MPa) (P < 0.05). In simulated gastric acid (HCl), PP-PMMA showed no significant difference in surface roughness compared to UN-PMMA (P = 0.29). However, in artificial saliva, PP-PMMA exhibited lower surface roughness (0.47±0.14μm) than UN-PMMA (0.56±0.08μm) (P < 0.05), indicating improved smoothness. Impact strength remained comparable between groups in both immersion conditions (P > 0.05). The presence of mesh between the layers restricted the ingress of saliva and HCl as was perceived with rougher surface in the external area.
Conclusion: PP reinforcement improved the flexural strength of PMMA in acidic environments and maintained surface roughness in acidic environments but did not significantly enhance impact strength. Polypropylene mesh reinforcement effectively reduced porosities and maintained structural integrity within the PMMA matrix. These findings suggested that polypropylene mesh reinforcement enhances the durability of denture base materials and benefits patients with gastroesophageal reflux condition.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370094 | PMC |
http://dx.doi.org/10.4103/jips.jips_130_25 | DOI Listing |
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Life Quality (LQ) Engineering Interest Group, School of Chemical and Environmental Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, Jiangsu Province 215123, China. Electronic address:
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Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.
Oral vaccination offers a promising strategy for controlling Helicobacter pylori infection, particularly in the face of rising antibiotic resistance and reinfection rates. In this study, we developed a chitosan nanoparticle-mediated oral DNA vaccine encoding the urease B subunit of H. pylori.
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Akkhraratchakumari Veterinary College, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
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View Article and Find Full Text PDFFood Res Int
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Fuzhou Institute of Oceanography, Minjiang University, Fuzhou 350108, China; Fujian Key Laboratory on Conservation and Sustainable Utilization of Marine Biodiversity, Minjiang University, Fuzhou, China. Electronic address:
This study employed high-pressure microfluidization (HPM) to facilitate the Maillard reaction between quinoa protein (QP) and dextran (DX), systematically examining the effects of various pressures on the conjugate's physicochemical properties. Fourier transform infrared spectroscopy confirmed the formation of QP-DX conjugates, characterized by a new peak at 1149 cm (covalent CN bond). Secondary and tertiary structure analyses revealed that HPM-assisted Maillard reaction partially unfolded QP molecules, enhancing conformational flexibility and interfacial properties.
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