Obesity and nutrition risk in patients admitted to intensive care after cardiac arrest: A multicentre cohort study.

Background: The double burden of malnutrition, defined as the co-existence of overnutrition with undernutrition, is increasing in prevalence globally. Yet, little is known about its impact on patients with cardiac arrest. We examined the association between malnutrition and outcomes in patients admitted to intensive care units (ICU) after cardiac arrest.

Mortality Trends Across Key Diagnostic Groups in Australian and New Zealand ICUs Over the Past 30 Years.

Objectives: The Australia and New Zealand Intensive Care Society (ANZICS) Adult Patient Database (APD) has been operational for 3 decades. It is important to understand how mortality outcomes have changed across diagnostic groups over time to facilitate the planning of future healthcare resources. We evaluated the trends in risk-adjusted mortality for ICU patients over the last 30 years.

The Varying Impact of Frailty With Increasing Body Mass Index on Survival Up To 3 Years After ICU Admission: A Retrospective Registry-Based Study.

Objectives: Frailty is associated with poorer outcomes in critical illness, but it is unclear if this relationship is consistent across different body mass index (BMI) levels.

Design: A retrospective multicentric registry-based observational study using the Australia New Zealand Intensive Care Society Adult Patient Database.

Setting: Criticallly ill patients admitted to 1170 ICUs between January 1, 2018, and March 31, 2022.

Structures and terahertz dynamics of an imidazolium-based ionic liquid on a gold electrode studied using surface-enhanced Raman scattering.

Room-temperature ionic liquids (RTILs) have been extensively studied for decades as a potential electrolyte alternative. The structural and dynamic properties of RTILs in an electrical double layer (EDL), formed at the electrode/electrolyte interface, differ from those in their bulk phase. Despite the importance of the interfacial properties of RTILs in electrical devices, such behaviours of denser ion structuring in EDL are poorly understood owing to the delicate anion-cation interplay among various intermolecular interactions such as Coulombic interaction, hydrogen bonding interaction, and π-type interaction.

Frailty and long-term survival of non-cancer patients admitted to intensive care after surgery: a retrospective multicentre cohort study.

Background: As the global population ages and older patients undergo surgery, understanding the association between frailty and postoperative outcomes is crucial to informed decision-making and patient care. There is a lack of research assessing the association between frailty and long-term outcomes in patients admitted to ICUs after surgery.

Methods: We conducted a multicentre retrospective cohort study using Australian and New Zealand Intensive Care Society Adult Patient Database, linked with the Australian National Death Index.

Suppression of fecal phenol production by oral supplementation of sesamol: inhibition of tyrosine phenol-lyase by sesamol.

Phenol is produced from dietary L-tyrosine by the action of tyrosine phenol-lyase (TPL) of gut bacteria and contributes to various physiological disorders, including skin diseases, certain cancers, and kidney dysfunction. We found that oral supplementation of sesamol (36 or 180 μg mL) for 14 days in mice significantly suppressed fecal phenol production. Fecal microbiota structure analysis in sesamol-supplemented and control groups revealed that their overall microbiota structures were indistinguishable.

Prevalence, Timing, and Predictors of Patients Who Had New and/or Updated Goals of Care While in the ICU: A Multicenter Retrospective Study.

Objectives: Timely documentation of patient-concordant goals of care (GOC) in the ICU aims to promote patient autonomy and patient-centered care where the harms of interventions outweigh the potential benefits. This study examined the prevalence, timing, and predictors of ICU patients undergoing new and updated GOC documentation events while in the ICU.

Design: Multicenter retrospective study.

The Effect of Real-Time Feedback Regarding the Center-of-Pressure Position on Patellofemoral Joint Loading During Double-leg Squatting.

Background: Exercise therapy is the cornerstone of patellofemoral (PF) pain management. However, whether squat exercises are therapeutic or detrimental depends on their technique and the resulting load on the PF joint.

Purpose/hypothesis: The purpose of this study was to investigate whether real-time feedback to position the center-of-pressure (COP) anteriorly could reduce the PF joint reaction force and stress during bodyweight double-leg squatting.

Long-term survival comparison of patients admitted to the intensive care unit following in-hospital cardiac arrest in perioperative and ward settings. A multicentre retrospective cohort study.

Purpose: Perioperative in-hospital cardiac arrests (Perioperative IHCAs) may have better outcomes than IHCAs in the ward (Ward IHCAs), due to enhanced monitoring and faster response. However, quantitative comparisons of their long-term outcomes are lacking, posing challenges for prognostication.

Methods: This retrospective multicentre study included adult intensive care unit (ICU) admissions from theatre/recovery or wards with a diagnosis of cardiac arrest between January 2018 and March 2022.

Calibrationless monocular vision musculoskeletal simulation during gait.

With computer vision technology and prediction of ground reaction forces (GRF), a previous study performed markerless motion capture and musculoskeletal simulation with two smartphones (OpenCap). A recent approach can reconstruct 3D human motion from a single video without calibration and it may further simplify the motion capture process. However it has not been combined with musculoskeletal simulation and the validity is unclear.

The impact of frailty on survival times up to one year among patients admitted to ICU with in-hospital cardiac arrest.

Background: In-hospital cardiac arrest (IHCA) is a serious medical emergency. When IHCA occurs in patients with frailty, short-term survival is poor. However, the impact of frailty on long-term survival is unknown.

Validity of muscle activation estimated with predicted ground reaction force in inverse dynamics based musculoskeletal simulation during gait.

The inverse dynamics based musculoskeletal simulation needs ground reaction forces (GRF) as an external force input. GRF can be predicted from kinematic data. However, the validity of estimated muscle activation using the predicted GRF has remained unclear.

FRailty in Australian patients admitted to Intensive care unit after eLective CANCER-related SURGery: a retrospective multicentre cohort study (FRAIL-CANCER-SURG study).

Background: The association between frailty and short-term and long-term outcomes in patients receiving elective surgery for cancer remains unclear, particularly in those admitted to the ICU.

Methods: In this multicentre retrospective cohort study, we included adults ≥16 yr old admitted to 158 ICUs in Australia from January 1, 2018 to March 31, 2022 after elective surgery for cancer. We investigated the association between frailty and survival time up to 4 yr (primary outcome), adjusting for a prespecified set of covariates.

Frailty and long-term survival among patients in Australian intensive care units with metastatic cancer (FRAIL-CANCER study): a retrospective registry-based cohort study.

Background: Recent advances in cancer therapeutics have improved outcomes, resulting in increasing candidacy of patients with metastatic cancer being admitted to intensive care units (ICUs). A large proportion of patients also have frailty, predisposing them to poor outcomes, yet the literature reporting on this is scarce. We aimed to assess the impact of frailty on survival in patients with metastatic cancer admitted to the ICU.

Impact of airline network on the global importation risk of mpox, 2022.

From 1 January 2022 to 4 September 2022, a total of 53 996 mpox cases were confirmed globally. Cases are predominantly concentrated in Europe and the Americas, while other regions are also continuously observing imported cases. This study aimed to estimate the potential global risk of mpox importation and consider hypothetical scenarios of travel restrictions by varying passenger volumes (PVs) via airline travel network.

Dose-response relationship between diarrhea quantity and mortality in critical care patients: A retrospective cohort study.

Background: Previous studies have shown that diarrhea, defined as a dichotomized cutoff, is associated with increased mortality of patients in intensive care units (ICUs). This study aimed to examine the dose-response relationship between the quantity of diarrhea and mortality in ICU patients with newly developed diarrhea.

Methods: We conducted this single-center retrospective cohort study.

Comparing the Clinical Frailty Scale and an International Classification of Diseases-10 Modified Frailty Index in Predicting Long-Term Survival in Critically Ill Patients.

Unlabelled: The Clinical Frailty Scale (CFS) is the most used frailty measure in intensive care unit (ICU) patients. Recently, the modified frailty index (mFI), derived from 11 comorbidities has also been used. It is unclear to what degree the mFI is a true measure of frailty rather than comorbidity.

Defining ICD-10 surrogate variables to estimate the modified frailty index: a Delphi-based approach.

Background: There are currently no validated globally and freely available tools to estimate the modified frailty index (mFI). The widely available and non-proprietary International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10) coding could be used as a surrogate for the mFI. We aimed to establish an appropriate set of the ICD-10 codes for comorbidities to be used to estimate the eleven-variable mFI.

Comparison of the predictive ability of clinical frailty scale and hospital frailty risk score to determine long-term survival in critically ill patients: a multicentre retrospective cohort study.

Background: The Clinical Frailty Scale (CFS) is the most commonly used frailty measure in intensive care unit (ICU) patients. The hospital frailty risk score (HFRS) was recently proposed for the quantification of frailty. We aimed to compare the HFRS with the CFS in critically ill patients in predicting long-term survival up to one year following ICU admission.

Sex difference in frontal plane hip moment in response to lateral trunk obliquity during single-leg landing.

Background: Lateral trunk obliquity during landing is a characteristic of anterior cruciate ligament (ACL) injuries in female athletes and affects their knee and hip kinetics and kinematics. However, it is unclear whether these effects differ between females and males. The purpose of this study was to compare the effects of lateral trunk obliquity on knee and hip kinetics and kinematics in females and males during single-leg landing.

[Validation Study on an Improved Quantitative Method for Aflatoxins in Foods].

As an analytical method for aflatoxins in foods, the analytical method based on the notification by the director of the Food Safety Department, Pharmaceutical and Food Safety Bureau, Ministry of Health, Labour and Welfare (August 16, 2011) has been established. In order to improve the operability and analytical performance of the conventional method, this study aimed to construct an improved method that optimized selection of immunoaffinity column (IAC) and purifying condition, and omitted evaporation after the purification with IAC. In the recovery test performed by adding 2.

Association between frailty and clinical outcomes in surgical patients admitted to intensive care units: a systematic review and meta-analysis.

Background: Preoperative frailty may be a strong predictor of adverse postoperative outcomes. We investigated the association between frailty and clinical outcomes in surgical patients admitted to the ICU.

Methods: PubMed, Embase, and Ovid MEDLINE were searched for relevant articles.