98%
921
2 minutes
20
Aiming at the requirement of space situational awareness on the full-domain and all-time coverage capability of low Earth orbit space targets and focusing on the design of a space-based space target awareness system, a space target awareness constellation design method based on simulation comparison is put forward. On the basis of systematically analyzing the distribution of space targets' orbits, the low Earth orbit space target surveillance mission mode, key indicators, and constraints of space target surveillance constellations are designed, and three space target surveillance constellation basic configurations are constructed. This paper randomly samples surveillance objects based on the stratified space target orbit distribution and selects a heterogeneous space target surveillance constellation in sun-synchronous morning-twilight orbit that meets the requirements of the surveillance mission model and capability by using simulations and comparisons. The experiments show that the constellation can provide a satisfactory observation arc segment for cataloging and orbiting more than 80% of low Earth orbit targets.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251904 | PMC |
http://dx.doi.org/10.3390/s25133977 | DOI Listing |
Exp Cell Res
September 2025
Tianjin Key Laboratory of Acute Abdomen Disease Associated Organ Injury and ITCWM Repair, Tianjin Nankai Hospital, Tianjin Medical University, Tianjin, 300100, China; Institute of Integrative Medicine for Acute Abdominal Diseases, Tianjin Nankai Hospital, Tianjin Medical University, Tianjin 300100,
The characteristic pathological change in chronic pancreatitis (CP) is pancreatic fibrosis. In the early stages of CP development, injured acinar cells induce the infiltration of inflammatory cells, followed by pancreatic stellate cell (PSC) activation. Activated PSC induce the deposition of extracellular matrix (ECM) and promote the development of pancreatic fibrosis.
View Article and Find Full Text PDFPrev Vet Med
September 2025
World Organisation for Animal Health (WOAH) Sub-Regional Representation for South East Asia, Bangkok 10400, Thailand.
Foot and mouth disease (FMD) remains endemic in several countries across Southeast Asia, China, and Mongolia (SEACFMD region), posing an ongoing threat to livestock and trade. This study aimed to investigate the epidemiological characteristics and analyze the spatial and temporal distribution of FMD outbreaks reported across the SEACFMD region. FMD outbreak and virus lineage data from 2015 to 2023 were utilized.
View Article and Find Full Text PDFMil Med
September 2025
School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia.
Introduction: Submarine environments pose unique challenges to maintaining physical activity and exercise routines due to confined spaces, demanding schedules, and limited resources. This study investigated submariners' physical activity patterns, sleep quality, and perceived exercise barriers in both land- and sea-based settings, with the goal of informing targeted health interventions.
Materials And Methods: Ethics approval was granted by the Defence Science and Technology Group and Edith Cowan University review panels.
Prog Neurobiol
September 2025
Age-Related and Brain Diseases Research Center, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; Biomedical Science Institute, Kyung Hee University, Seoul, Republi
Lumbar spinal stenosis (LSS) is one of the most common spinal disorders in elderly people and is often accompanied by neuropathic pain. Although our previous studies have demonstrated that infiltrating macrophage contribute to chronic neuropathic pain in LSS rat model, the molecular mechanisms underlying macrophage activation and infiltration have not been fully elucidated. In this study, we examined the critical role of platelet-derived growth factor receptor (PDGFR) signaling pathway in neuropathic pain associated with macrophage infiltration and activation in LSS rats.
View Article and Find Full Text PDFCurr Opin Immunol
September 2025
Univ. Grenoble Alpes, CNRS, CEA, UMR5075, IBS, Laboratoire d'Immunologie, CHU Grenoble Alpes, Grenoble, France.
The complement system plays a paradoxical role in systemic lupus erythematosus physiopathology, acting both as a protective mechanism and as a driver of tissue injury, depending on disease stage. Neutrophil extracellular traps (NETs) further exacerbate disease activity by promoting complement activation and autoantigen exposure, forming an amplifying inflammatory loop. Lupus nephritis remains challenging to monitor using conventional complement biomarkers such as CH50, C3, and C4; the utility of anti-C1q, anti-ficolin, and anti-C1s antibodies, along with tissue-based markers such as renal C4d and C5b-9 deposits, as markers of disease activity and prognosis, is discussed.
View Article and Find Full Text PDF