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Mechanical defects and sensor failures can substantially undermine the reliability of low-cost sensors, especially in applications where measurement inaccuracies or malfunctions may lead to critical outcomes, including system control disruptions, emergency scenarios, or safety hazards. To overcome these challenges, this paper presents a novel Self-X architecture with sensor redundancy, which incorporates dynamic calibration based on multidimensional mapping. By extracting reliable sensor readings from imperfect or defective sensors, the system utilizes Self-X principles to dynamically adapt and optimize performance. The approach is initially validated on synthetic data from tunnel magnetoresistance (TMR) sensors to facilitate method analysis and comparison. Additionally, a physical measurement setup capable of controlled fault injection is described, highlighting practical validation scenarios and ensuring the realism of synthesized fault conditions. The study highlights a wide range of potential TMR sensor failures that compromise long-term system reliability and demonstrates how multidimensional mapping effectively mitigates both static and dynamic errors, including offset, amplitude imbalance, phase shift, mechanical misalignments, and other issues. Initially, four individual TMR sensors exhibited mean absolute error (MAE) of 4.709°, 5.632°, 2.956°, and 1.749°, respectively. To rigorously evaluate various dimensionality reduction (DR) methods, benchmark criteria were introduced, offering insights into the relative improvements in sensor array accuracy. On average, MAE was reduced by more than 80% across sensor combinations. A clear quantitative trend was observed: for instance, the MAE decreases from 4.7°-5.6° for single sensors to 0.111° when the factor analysis method was applied to four sensors. This demonstrates the concrete benefit of sensor redundancy and DR algorithms for creating robust, fault-tolerant measurement systems.
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http://dx.doi.org/10.3390/s25133841 | DOI Listing |
Medicine (Baltimore)
September 2025
Nanchang Bright Eye Hospital, Nanchang, Jiangxi, China.
Introduction: This bibliometric analysis aims to explore global trends, research hotspots, and future directions in multidrug resistance of multiple myeloma (MM), providing insights for overcoming resistance mechanisms and optimizing therapeutic strategies.
Methods: We analyzed 3300 publications indexed in the Web of Science Core Collection (2015-2024) using CiteSpace and VOSviewer. Multidimensional evaluations of countries/regions, institutions, authors, journals, and keywords were conducted, supplemented by visual network mapping to elucidate research dynamics and collaborative patterns.
Food Res Int
November 2025
School of Preclinical Medicine, Chengdu University, Chengdu, Sichuan 610106, China. Electronic address:
Background: Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disease characterized by insulin resistance and progressive decline in pancreatic beta cell function. It is a public health problem of great magnitude that has been increasing globally over the last 4 decades. The latest research has found that sugar-sweetened beverages (SSBs), as an important dietary risk factor, are closely related to the occurrence and development of T2DM.
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August 2025
College of Pharmacy, Zunyi Medical University, Zunyi, 563006, China.
Background: Epigenetic regulation constitutes critical molecular mechanisms underlying the pathogenesis of diabetes and disease progression. While substantial mechanistic investigations exist, the field lacks systematic mapping of research trends, collaborative networks, and emerging frontiers.
Objectives: To conduct the first comprehensive bibliometric evaluation of epigenetic studies in diabetes mellitus and its complications (2014-2024), identifying key research domains, international collaboration patterns, and innovative investigative directions to inform strategic research planning and highlight opportunities for innovative therapeutic approaches.
Nat Methods
September 2025
Brain Mind Institute, School of Life Sciences, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland.
Embryo development entails the formation of anatomical structures with distinct biochemical compositions. Compared with the wealth of knowledge on gene regulation, our understanding of metabolic programs operating during embryogenesis is limited. Mass spectrometry imaging (MSI) has the potential to map the distribution of metabolites across embryo development.
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