98%
921
2 minutes
20
This case series was aimed primarily at evaluating the outcomes of a reconstructive technique employing autogenous bone grafting using maxillary tuberosity (MT) donor sites for the management of extraction sockets adjacent to large incisive foramena (IFs) in the anterior maxillary region, with the purpose of addressing challenges associated with implant placement. In this series of four cases, we applied a reconstructive technique utilizing autogenous bone grafting using MT donor sites. Patients underwent a postoperative maintenance program, clinical examinations, and completion of a questionnaire to assess changes in the neurosensory function of the nasopalatine nerve. Study outcomes included the extent of bone reconstruction, postoperative neurosensory function of the nasopalatine nerve, and overall patient satisfaction. Cases were followed for a mean of 23.5±0.5 months. The technique consistently resulted in predictable bone reconstruction, either with delayed or immediate implantation and provisionalization. IF enucleation and reconstruction of the damaged extraction sockets resulted in no abnormal postoperative pain or paresthesia, and yielded high patient satisfaction. The use of autogenous bone grafts from the MT provides an optimal and simple solution for the management of extraction sockets adjacent to large IFs. Our findings illustrate the potential efficacy of this technique in complex scenarios associated with high esthetic implications, which should be further evaluated in future clinical trials.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.11607/prd.7376 | DOI Listing |
Tissue Eng Part B Rev
September 2025
The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.
The reconstruction of critical-sized bone defects remains a challenging clinical problem. At present, the implantation of autogenous and allogeneic grafts is the main clinical treatment strategy but faces some drawbacks, such as inadequate source, donor site-related complications, and immune rejection, driving researchers to develop artificial bone substitutes based on distinct materials and fabrication technologies. Among the bone substitutes, bioceramic-based substitutes exhibit a remarkable biocompatibility, which can also be designed to degrade concomitantly with the formation of new bone.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, 430070, PR China. Electronic address:
Due to the poor regeneration ability of cartilage tissue, the design and fabrication of permanent hydrogel cartilage scaffolds with mechanical properties matching is still an urgent challenge. In this study, we propose an "inner swelling-outer restraint" strategy to construct Janus hydrogel for pressure-bearing cartilage replacement, which is inspired by the "Lamina-splendens" structure of cartilage. As a proof of concept, the poly(vinyl alcohol)/carboxymethyl cellulose sodium (PVA/CMCNa) layer is designed to capture more fluid by introducing negatively charged aggregates, while the macromolecular conformation of the PVA/MoS layer can be densified through wet annealing, thereby increasing the liquid permeation resistance of the PVA/CMCNa layer.
View Article and Find Full Text PDFJ Endod
September 2025
Department of Periodontology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. Electronic address:
Severe periapical cysts frequently result in tooth loss with concomitant severe alveolar bone destruction, precluding immediate implant placement. Autogenous tooth transplantation (ATT), which involves transplanting the patient's own tooth to the recipient site, offers a biological approach to reconstruct both the dentition and supporting bone structures. This report presents a 25-year-old female with a mobile, discolored maxillary right lateral incisor (#12) exhibiting grade 3 mobility due to a large periapical cyst (extending to #14 on CBCT) with root developmental arrest, secondary to Oehlers type II dens invaginatus.
View Article and Find Full Text PDFMedicine (Baltimore)
August 2025
Department of Orthopaedic Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Insufficiency periprosthetic fractures after total knee arthroplasty are uncommon, typically nontraumatic events; however, clinical outcome data on their surgical management remain limited. We retrospectively reviewed 21 patients (18 women, 3 men; mean age = 76 years) who sustained femoral or tibial insufficiency periprosthetic fractures between November 2016 and January 2022 and underwent revision total knee arthroplasty with stemmed components augmented by bulk femoral-head allografts and autologous bone graft. Five patients with preoperative valgus alignment presented medial condylar fractures, whereas sixteen patients with varus deformity exhibited ten lateral and 6 medial condylar fractures.
View Article and Find Full Text PDFUnfallchirurgie (Heidelb)
August 2025
Klinik für Unfallchirurgie und Orthopädie, BG Klinik Ludwigshafen, Ludwig-Guttmann-Str. 13, 67071, Ludwigshafen am Rhein, Deutschland.
Bone defects in the limbs may result from trauma, debridement during osteitis or pseudarthrosis resection or tumors [1]. Treating bone defects of the femur and tibia poses a substantial challenge in trauma surgery and orthopedics. Interdisciplinary orthoplastic treatment combined with soft tissue reconstruction is often necessary to preserve the extremity and its function.
View Article and Find Full Text PDF