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Concern around the emergence of zoonoses with pandemic potential has fuelled significant foreign engagement with domestic infectious disease surveillance and response systems across Africa. These international efforts at augmentation have likely been hampered, however, by an inattention to how such systems actually manifest on the ground and the critical activities and undertakings that take place outside of official structures and protocols. Such deviations from official protocols have previously been treated as inherently detrimental to public service delivery. A growing body of anthropological scholarship arising out of west and east Africa, however, has revealed that such deviations are often crucial to realising some core function or facet of it. Further, these apparent acts of discretion can represent broadly standardised sets of practices and structures that can be elucidated through interviews and observation.In this paper, we present an ethnographic account of the investigations into a suspected outbreak of a newly emerging zoonosis in the Brong Ahafo Region of Ghana between 2010 and 2016. By following the unfolding of the responses to the Brong Ahafo Region outbreak and drawing on observations from contemporaneous zoonotic outbreaks in West Africa, we elucidate the kinds of unofficial professional practices and shared visions of public service delivery which shape, and frequently augment, national responses to suspected newly emerging infectious diseases. The paper advances recent anthropological work on practical norms by applying them to emerging infectious disease control systems and considering the role of professional ethos in coordinating their use. The paper also clarifies the nature and utility of such unofficial activities for foreign would-be reformers of domestic surveillance and response systems in Africa, potentially enabling more effective transnational engagement with, and strengthening of, these critical systems for emerging infectious disease control.
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http://dx.doi.org/10.1136/bmjgh-2024-017717 | DOI Listing |
JAMA Pediatr
September 2025
Department of Health Policy and Management, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Importance: For the first time in nearly 2 decades, the US infant mortality rate has increased, coinciding with a rise in overdose-related deaths as a leading cause of pregnancy-associated mortality in some states. Prematurity and low birth weight-often linked to opioid use in pregnancy-are major contributors.
Objective: To assess the health and economic impact of perinatal opioid use disorder (OUD) treatment on maternal and postpartum health, infant health in the first year of life, and infant long-term health.
mBio
September 2025
Flinders Accelerator for Microbiome Exploration, College of Science and Engineering, Flinders University, Adelaide, South Australia, Australia.
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) ESKAPE pathogens pose a significant global health threat due to their ability to evade antibiotics through intrinsic and acquired mechanisms. These bacteria, including , , , , , and species, evade antibiotics through intrinsic and adaptive mechanisms. Common strategies include capsule formation, biofilm, β-lactamase production, and efflux activity.
View Article and Find Full Text PDFMicrobiol Spectr
September 2025
Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
is a commensal bacterium that colonizes the gut of humans and animals and is a major opportunistic pathogen, known for causing multidrug-resistant healthcare-associated infections (HAIs). Its ability to thrive in diverse environments and disseminate antimicrobial resistance genes (ARGs) across ecological niches highlights the importance of understanding its ecological, evolutionary, and epidemiological dynamics. The CRISPR2 locus has been used as a valuable marker for assessing clonality and phylogenetic relationships in .
View Article and Find Full Text PDFMicrobiol Spectr
September 2025
King Abdullah International Medical Research Center, Jeddah, Saudi Arabia.
Recently, to achieve cure, physicians have been resorting to overuse or misuse of antimicrobials to treat resistant infections, leading to the emergence of further resistant organisms. To overcome this issue, antimicrobial guidelines have been developed. Nevertheless, recently, controversy regarding the effect of adherence to antimicrobial guidelines on patient outcomes has been raised.
View Article and Find Full Text PDFDiabetes Obes Metab
September 2025
Phase I Clinical Trial Research Ward, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, People's Republic of China.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is an emerging global health concern, and its presence increases the risk of multi-system diseases. This study aimed to investigate the multimorbidity trajectories of chronic diseases in people living with MASLD.
Methods: We identified 137 859 MASLD patients in UK Biobank and used 'propensity score matching' to match an equal number of non-MASLD controls.