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Article Abstract
Aims: To investigate the association of cumulative childhood adversity with frailty and whether this association differs across socioeconomic status.
Methods: The study included 6100 middle-aged and older adults in China from the CHARLS-2014 life course survey and the CHARLS-2015 survey. A frailty index (FI) was constructed from 39 questionnaire items, with higher values indicating higher frailty.
Results: Participants who experienced four or more childhood adversities had a higher risk of frailty than those who never experienced childhood adversity in the fully adjusted model (OR: 2.95, 95 % CI: 2.24-3.88; β = 0.053; 95 % CI, 0.044-0.062) (p trend < 0.01). A significant dose-response relationship was observed between cumulative childhood adversity and risk of frailty. Socioeconomic status was not found to modify the association of cumulative childhood adversity with frailty.
Conclusions: Developing effective public health strategies to reduce the incidence of adverse childhood experiences are necessary to prevent adverse health outcomes across the life course.
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| http://dx.doi.org/10.1016/j.gerinurse.2025.103459 | DOI Listing |
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