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This study investigated the impact of situational factors (team quality, match outcomes, and match location) on pitch-passing networks in the English Premier League. We analysed 295,901 possessions across 380 matches using a 7 × 7 grid system. For each pitch-passing network we calculated the degree centrality, the closeness centrality, and the betweenness centrality. A Mann-Whitney U test was employed to examine differences in these centrality measures across situational factors. Results indicated that strong teams demonstrated significantly higher degree centrality in midfield and centre-to-forward zones, and maintained superior closeness centrality across the pitch, particularly in central zones, while weak teams showed higher betweenness centrality on pitch flanks. Winning teams exhibited small differences in degree and closeness centrality across multiple zones, with notably medium differences in forward areas, and stronger closeness centrality throughout the pitch. At the same time, home teams demonstrated dominance in forward areas through degree centrality, while away teams showed higher activity in defensive baseline zones. Consequently, these findings demonstrate the systematic influences of situational factors on spatial passing patterns, providing empirical evidence for tactical adaptation. Coaches can leverage these insights to optimise passing strategies in critical areas such as midfield and forward zones to enhance offensive efficiency.
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http://dx.doi.org/10.1038/s41598-025-04507-1 | DOI Listing |
Curr Alzheimer Res
September 2025
Department of Neurology, the Wuxi No. 2 People's Hospital, Jiangnan University Medical Center, Wuxi, Jiangsu Province, China.
Introduction: The complement receptor 1 (CR1) gene is identified as the one closely associated with Alzheimer's disease (AD). However, there has been no exploration of the imaging alterations associated with the CR1 gene in AD patients of the Han population. The purpose of this study is to investigate the association between the rs6656401 mutation and neuroimaging variations in Han AD patients.
View Article and Find Full Text PDFActa Psychol (Amst)
September 2025
Wannan Medical College, Wuhu, Anhui, China. Electronic address:
Background: Mental health issues among middle school students are closely associated with life events and childhood trauma experiences. However, the interactive pathways among these three factors remain unclear. Based on network analysis, this study constructs a network model to identify core nodes (high-intensity symptoms) and bridge nodes (cross-group associated symptoms), aiming to reveal their interaction mechanisms and provide a foundation for targeted interventions in adolescent mental health.
View Article and Find Full Text PDFWorld Neurosurg
September 2025
Department of Neurosurgery, New York University Langone Medical Center, New York, NY.
Objective: Mentorship and training relationships shape the careers and influence of neurosurgeons. Network analysis can reveal structural characteristics and key individuals who support network connectivity and drive the field's development. This endeavor analyzed the US-based neurosurgical training network derived from NeurosurGen.
View Article and Find Full Text PDFSleep Med
August 2025
Department of Radiology Imaging Center, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, PR China. Electronic address:
Objective: This multicenter study aimed to investigate resting-state brain functional alterations in patients with type 2 diabetes mellitus (T2DM) comorbid with obstructive sleep apnea (OSA), and to elucidate the underlying neural mechanisms.
Methods: A total of 139 participants were enrolled from two centers, including 48 healthy controls (HCs), 46 T2DM patients, and 45 T2DM with OSA patients. Resting-state functional magnetic resonance imaging (rs-fMRI) was used to assess brain function using degree centrality (DC), amplitude of low-frequency fluctuation (ALFF), and seed-based functional connectivity (FC).
EBioMedicine
September 2025
Department of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Linus Biotechnology, Inc., North Brunswick Township, NJ, USA. Electronic address:
Background: Amyotrophic lateral sclerosis (ALS) is a rare motor neurodegenerative disorder and is predominantly diagnosed in older adults. Altered levels of essential and toxic elements have been implicated in ALS pathophysiology; however, little is known about the longitudinal biodynamic patterns of these elements in patients with ALS.
Methods: Using a single individual hair strand, we generated time series data of 400-800 time points approximately at 2 to 4 hourly resolution on 17 elemental intensities in ALS-positive cases and ALS-negative controls from a national collection and a regional centre in the US (on a total sample of 391, with 295 cases and 96 controls, with median age at hair collection over 60 years).