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Ultrasound imaging can distinctly display the morphology and structure of internal organs within the human body, enabling the examination of organs like the breast, liver, and thyroid. It can identify the locations of tumors, nodules, and other lesions, thereby serving as an efficacious tool for treatment detection and rehabilitation evaluation. Typically, the attending physician is required to manually demarcate the boundaries of lesion locations, such as tumors, in ultrasound images. Nevertheless, several issues exist. The high noise level in ultrasound images, the degradation of image quality due to the impact of surrounding tissues, and the influence of the operator's experience and proficiency on the determination of lesion locations can all contribute to a reduction in the accuracy of delineating the boundaries of lesion sites. In the wake of the advancement of deep learning, its application in medical image segmentation is becoming increasingly prevalent. For instance, while the U-Net model has demonstrated a favorable performance in medical image segmentation, the convolution layers of the traditional U-Net model are relatively simplistic, leading to suboptimal extraction of global information. Moreover, due to the significant noise present in ultrasound images, the model is prone to interference. In this research, we propose an Attention Residual Network model (ARU-Net). By incorporating residual connections within the encoder section, the learning capacity of the model is enhanced. Additionally, a spatial hybrid convolution module is integrated to augment the model's ability to extract global information and deepen the vertical architecture of the network. During the feature fusion stage of the skip connections, a channel attention mechanism and a multi-convolutional self-attention mechanism are respectively introduced to suppress noisy points within the fused feature maps, enabling the model to acquire more information regarding the target region. Finally, the predictive efficacy of the model was evaluated using publicly accessible breast ultrasound and thyroid ultrasound data. The ARU-Net achieved mean Intersection over Union (mIoU) values of 82.59% and 84.88%, accuracy values of 97.53% and 96.09%, and F1-score values of 90.06% and 89.7% for breast and thyroid ultrasound, respectively.
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http://dx.doi.org/10.1038/s41598-025-04086-1 | DOI Listing |
Anal Chim Acta
November 2025
Department of Breast Surgery, General Surgery Center, First Hospital of Jilin University, Changchun, PR China. Electronic address:
Background: Breast-conserving surgery (BCS) is the primary surgical approach for patients with breast cancer. The accurate determination of surgical margins during BCS is critical for patient prognosis; however, time constraints and limitations in current pathological techniques often prevent pathologists from performing this assessment intraoperatively. The inability to reliably assess margins during surgery can lead to incomplete tumor removal and the need for additional surgeries.
View Article and Find Full Text PDFEur J Vasc Endovasc Surg
September 2025
School of Health and Medical Sciences, City St George's University of London, London, UK; St George's Vascular Institute, St George's Hospital, London, UK; Department of Surgery and Cancer, Imperial College London, London, UK. Electronic address:
Objective: Sex specific anatomical differences may contribute to observed disparities in outcomes and suitability for endovascular aneurysm repair (EVAR) between men and women with abdominal aortic aneurysms (AAAs). This study aimed to assess these differences using fully automated volume segmentation (FAVS) and explore implications for EVAR suitability.
Methods: This was a retrospective, multicentre cohort study of patients undergoing elective AAA repair between 2013 and 2023 in three UK tertiary centres.
Surv Ophthalmol
September 2025
Paris Cité University, Department of Ophthalmology, Lariboisière University Hospital, APHP, F-75010 Paris, France.
Dome-shaped macula (DSM) is a distinctive anatomical entity characterized by an inward convexity of the macula, initially described in highly myopic eyes within posterior staphyloma, but it is now recognized as occurring across a broader spectrum of refractive conditions, including mild myopia and even emmetropia. Since its initial description in 2008, advances in imaging technologies and longitudinal studies have significantly improved our understanding of DSM. This review analyzed the recent literature, focusing on publications from the last 10 years.
View Article and Find Full Text PDFAnn Anat
September 2025
Department of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Greece; "VARIANTIS" Research Laboratory, Department of Clinical Anatomy, Mazovian Academy in Plock, Poland.
Background: The vertebral artery (VA) undergoes a critical anatomical transition as it pierces the dura mater at the craniocervical junction. Precise knowledge of dural penetration patterns and angulation is essential for diagnostic imaging, neurosurgical planning, and minimizing iatrogenic risk in posterior fossa procedures.
Methods: This retrospective imaging study evaluated 100 adult patients who underwent 1.
Prev Vet Med
September 2025
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 'Bruno Ubertini' (IZSLER), Via Bianchi 7/9, Brescia 25124, Italy. Electronic address:
Accurate classification of lung lesions at necropsy is crucial for guiding the diagnostic process and ensuring effective management of porcine respiratory diseases. Post-mortem inspection of the lungs during slaughter also provides valuable insights into disease occurrence, offering useful feedback on the efficacy of on-farm prevention and control strategies. However, manual assessment protocols may be impaired by high slaughtering speeds and low inter-rater agreement, which limits continuous data collection and hinders comparability.
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