Publications by authors named "Matteo Recchia"
Accurate classification of lung lesions at necropsy is crucial for guiding the diagnostic process and ensuring effective management of porcine respiratory diseases. Post-mortem inspection of the lungs during slaughter also provides valuable insights into disease occurrence, offering useful feedback on the efficacy of on-farm prevention and control strategies. However, manual assessment protocols may be impaired by high slaughtering speeds and low inter-rater agreement, which limits continuous data collection and hinders comparability.
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- The study investigates the presence of Helicobacter species, specifically H. pylori and "Candidatus H. bovis," in the abomasum of dairy cattle and sheep in Northern Italy, focusing on their potential role in gastric diseases.
- Out of 25 dairy cows and 24 sheep examined, 96% of the bovine samples and 42% of the ovine samples tested positive for Helicobacteraceae, with "Candidatus H. bovis" found predominantly in the bovine pyloric mucosa.
- The findings suggest that "Candidatus H. bovis" is common in cattle but not linked to inflammation, indicating a specific adaptation to bovine hosts, and the potential for cattle and sheep
The present study retrospectively analyzed the infectious agents associated with 829 abortion outbreaks occurring from 2011 to 2021 in northern Italy. Foetuses were subjected to necropsies, and organ samples were analyzed by direct PCR to screen for six swine pathogens. In 42.
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- Respiratory diseases in pigs lead to production losses and higher use of antibiotics on farms.
- An analysis of lung and pleural lesion scores from pig carcasses at slaughterhouses in Italy was conducted to assess the effectiveness of antimicrobial use (AMU) on 113 farms.
- Significant correlations were found between lung scores and the use of critical antimicrobials, suggesting that monitoring these lesions can help improve antibiotic management and reduce unnecessary usage.
Respiratory diseases significantly affect intensive pig farming, causing production losses and increased antimicrobial use. Accurate classification of lung lesions is crucial for effective diagnostics and disease management. The integration of non-destructive and rapid techniques would be beneficial to enhance overall efficiency in addressing these challenges.
View Article and Find Full Text PDFBrain metastasis (BM) represents a clinical challenge for patients with advanced HER2 + breast cancer (BC). The monoclonal anti-HER2 antibody trastuzumab (TZ) improves survival of BC patients, but it has low central nervous system penetrance, being ineffective in treating BM. Previous studies showed that ferritin nanoparticles (HFn) may cross the blood brain barrier (BBB) through binding to the transferrin receptor 1 (TfR1).
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