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Background: Since the Trauma and Injury Severity Score (TRISS) was first developed in 1987, it has been widely used to predict trauma outcomes. However, numerous attempts have been made to adjust coefficients or develop new prediction models, as TRISS may not align with the local conditions. This study aimed to develop a Korean-TRISS (K-TRISS) model suitable for the Korean population.
Methods: We analyzed data from adult patients with blunt trauma in the Korea Trauma Data Bank (KTDB) from January 2017 to December 2021. A new set of TRISS coefficients (K-TRISS-1) was derived from the study data using a logistic regression method. We compared the predictive ability of the K-TRISS-1 with the previous Major Trauma Outcome Study (MTOS) in 1987 and the National Trauma Data Bank (NTDB) model in 2009. The predictive power of the models was evaluated with the area under receiver operating characteristic (AUROC) curves, and the validity was evaluated with the C-statistic and bootstrap verification methods. Additionally, we enhanced the model construction (K-TRISS-2) by converting the age variable from a categorical format to a continuous one.
Results: Overall, 128,534 cases were included in the statistical analysis. The comparison of AUROC values indicated that K-TRISS-1 (0.9232) outperformed MTOS (0.9210) and NTDB (0.9190), with their 95% confidence intervals showing some tendency (0.9196-0.9267, 0.9200-0.9230, and 0.9180-0.9210, respectively). However, K-TRISS-2 (0.9336, 0.9305-0.9367) had a significantly higher AUROC value compared to those of the others and showed excellent predictive power in the C-statistic and bootstrap tests.
Conclusion: This study proposes the K-TRISS model, derived from the KTDB, which does not significantly differ from the previous models in terms of predictive power. Furthermore, we were able to construct a model demonstrating improved predictive power when converting age to a continuous variable.
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http://dx.doi.org/10.3346/jkms.2025.40.e122 | DOI Listing |
Nutr Clin Pract
September 2025
Nutrition Department, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Background: Early diagnosis of malnutrition is essential for rapid decision-making regarding nutrition care to improve patient outcomes. We aimed to evaluate the prevalence of malnutrition using the Global Leadership Initiative on Malnutrition (GLIM) criteria and to assess the association of GLIM with 1-year mortality and length of hospital stay (LOS) in patients admitted to an emergency department (ED).
Methods: Prospective cohort study conducted in the ED of a university hospital.
Mol Psychiatry
September 2025
Department of Child and Adolescent Psychiatry and Psychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.
Epigenetic processes, such as DNA methylation, show potential as biological markers and mechanisms underlying gene-environment interplay in the prediction of mental health and other brain-based phenotypes. However, little is known about how peripheral epigenetic patterns relate to individual differences in the brain itself. An increasingly popular approach to address this is by combining epigenetic and neuroimaging data; yet, research in this area is almost entirely comprised of cross-sectional studies in adults.
View Article and Find Full Text PDFJ Electrocardiol
August 2025
Department of Cardiology, Kırşehir Ahi Evran Training and Research Hospital, Kırşehir, Turkey. Electronic address:
Background: Ischemia with non-obstructive coronary arteries (INOCA) represents a diagnostic and therapeutic challenge, often related to coronary microvascular dysfunction (CMD). Identifying non-invasive electrocardiographic markers that predict ischemia in this population remains a clinical priority. P-wave peak time (PWPT), reflecting atrial conduction delay, has been linked to ischemic pathophysiology.
View Article and Find Full Text PDFGait Posture
September 2025
School of Business, Social and Decision Sciences, Constructor University Bremen, Constructor University, Campus Ring 1, Bremen 28759, Germany.
Background: Age-related declines in dynamic balance and cognitive control increase fall risk in older adults (OA). Non-invasive brain stimulation, such as anodal transcranial direct current stimulation (a-tDCS), may enhance training outcomes. However, it remains unclear whether stimulation over motor or prefrontal regions is more effective for improving dynamic balance training (DBT) in OA.
View Article and Find Full Text PDFNeuropsychologia
September 2025
Department of Experimental Psychology and Oxford Centre for Human Brain Activity, Wellcome Centre for Integrative Neuroimaging, Department of Psychiatry, University of Oxford, Oxford, United-Kingdom. Electronic address:
Models of memory consolidation propose that newly acquired memory traces undergo reorganisation during sleep. To test this idea, we recorded high-density electroencephalography (EEG) during an evening session of word-image learning followed by immediate (pre-sleep) and delayed (post-sleep) recall. Polysomnography was employed throughout the intervening night, capturing time spent in different sleep stages.
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