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The escalating prevalence of cardiovascular diseases globally call for a low-cost monitoring technology for an immediate intervene and diagnoses. Advance multiplexed biosensors reinforced by graphene derivatives marks a significant progression in the field of cardiovascular health assessments. The graphene derived biosensors are designed specifically for fast detection of cardiac biomarkers with high precision to evaluate cardiovascular health. The graphene biocompatibility and fast signal transduction electronic properties provide an ideal foundation for the multiplexed technology. Despite the substantial potential of this multiplexed technologies, there remains a pressing need for further research and development to fully harness their capabilities in clinical environments. This study underscores the critical role of these biosensors in point of care applications and reviews the current landscape of research, highlighting significant progress made in graphene-based transduction and the recent trends in graphene production which give impact on biosensors performance. Key components are discussed include the assessment of vital cardiac biomarkers and the evolution of multiplex biosensing strategies that utilizes graphene nanomaterials. In summary, this review provides a comprehensive overview of the latest advancements in multi-analyte detection for cardiac healthcare. It outlines the key challenges encountered while proposing potential strategies to improve the effectiveness of multiplex biosensing platforms, thereby supporting the advancement of cardiac diagnostics. The potential of multiplexed biosensing technology leads to enhance diagnostic capabilities while reducing healthcare costs represents a significant advancement in cardiovascular healthcare, particularly for point-of-care applications.
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http://dx.doi.org/10.1080/10408347.2025.2525201 | DOI Listing |
Chem Commun (Camb)
September 2025
State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China.
We report the synthesis of three-dimensional (3D) graphene/mesoporous carbon/ZIF-derived microporous carbon (G/MC/ZDC-A) heterostructures through an interface-reinforced assembly. This hierarchical architecture synergistically integrates 2D graphene nanosheets with 0D ZDC nanoparticles a mesoporous carbon "binder", effectively mitigating the agglomeration issue while establishing continuous charge transport pathways. When configurated as symmetric supercapacitors with EMIMBF electrolyte, the obtained G/MC/ZDC-A demonstrates decent capacitive performance: a high specific capacitance (240 F g at 0.
View Article and Find Full Text PDFACS Macro Lett
September 2025
State Key Laboratory of Synergistic Chem-Bio Synthesis, Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, P. R. China.
Graphene-based films are highly valued for their superior conductivity, thermal stability, and mechanical strength, yet their brittleness and low ductility limit their full potential. Current toughening strategies for graphene-based composites mainly focus on interfacial reinforcement between polymers and graphene substrates. However, research on energy dissipation arising from the intrinsic properties of polymers remains limited.
View Article and Find Full Text PDFRSC Adv
August 2025
Department of Environmental Science and Disaster Management, Noakhali Science and Technology University Bangladesh.
Methylene blue (MB) remains one of the most resilient contaminants in industrial wastewater which presents serious threats to both environmental integrity and human health. Its high chemical stability and resistance to natural degradation render most conventional treatment methods ineffective. As such, this study aimed to develop a multifunctional nanocomposite membrane that mitigates membrane fouling, enhances dye separation, and improves water permeability.
View Article and Find Full Text PDFSci Rep
September 2025
Petrolum Applications Department, Egyptian Petroleum Research Institute (EPRI), Ahmed El-Zomer, Nasr City, Cairo, Egypt.
An innovative composite membrane was developed by combining polyvinylidene fluoride (PVDF) with graphene oxide (GO), titania (TiO), and silica (SiO) nanoparticles (PGTS). This innovative membrane was created using solution casting and electrospinning techniques to enhance its surface area and hydrophilic characteristics, while incorporating photocatalytic properties for light-induced oil decomposition. The membrane structure was examined by scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR).
View Article and Find Full Text PDFChem Sci
August 2025
Department of Applied Chemistry, School of Science and Technology, Meiji University 1-1-1 Higashimita, Tama-ku Kawasaki Kanagawa 214-8571 Japan
Herein, we report the synthesis and characterization of π-conjugated macrocycles, with diameters over 2.4 nanometers, composed of biphenylene and butadiyne units. Specifically, biphenylene-2,7-diyl-butadiyne-1,4-diyl (BB) macrocycles were synthesized the intermolecular Hay coupling reaction of a 2,7-diethynylbiphenylene derivative.
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