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More than 30% of reproductive-age women are obese or overweight. Intermittent fasting (IF), including alternate-day fasting (ADF), time-restricted eating (TRE), and 5:2 fasting, has been shown to reduce obesity-related metabolic diseases and is gaining popularity among women. However, the impact of ADF and TRE on female reproductive health remains controversial, given that women's reproductive physiology is particularly sensitive to environmental factors. In this summary we explored the effects of IF on female reproduction and on the basis of our findings we propose that TRE could be a feasible and acceptable lifestyle intervention for modifying eating behaviors before and potentially during pregnancy, and we also outline the potential mechanisms involved.
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http://dx.doi.org/10.1093/nutrit/nuaf107 | DOI Listing |
J Nutr Biochem
September 2025
Multicentric Postgraduate Program in Physiological Sciences, SBFis, São Paulo State University (UNESP), School of Dentistry, Araçatuba, SP, Brazil; Department of Basic Sciences, São Paulo State University (UNESP), School of Dentistry, Araçatuba, SP, Brazil; Postgraduate Program in Sciences, Pedi
Studies indicate that dietary patterns influence the function and redox balance of salivary glands. This study examined the effects of intermittent fasting (IF) on the function, histological structure, and redox balance of the salivary glands. Twenty 12-weeks-old male Wistar rats were randomized into two groups: ad libitum (AL), with continuous access to water and chow, and IF, subjected to 24-hour fasting on alternate days for 12 weeks.
View Article and Find Full Text PDFSleep Med
August 2025
Department of Radiology Imaging Center, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, PR China. Electronic address:
Objective: This multicenter study aimed to investigate resting-state brain functional alterations in patients with type 2 diabetes mellitus (T2DM) comorbid with obstructive sleep apnea (OSA), and to elucidate the underlying neural mechanisms.
Methods: A total of 139 participants were enrolled from two centers, including 48 healthy controls (HCs), 46 T2DM patients, and 45 T2DM with OSA patients. Resting-state functional magnetic resonance imaging (rs-fMRI) was used to assess brain function using degree centrality (DC), amplitude of low-frequency fluctuation (ALFF), and seed-based functional connectivity (FC).
Cell Rep Med
August 2025
Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia; Lifelong Health, South Australian Health and Medical Research Institute, Adelaide, SA, Australia; Robinson Research Institute, Adelaide, SA, Australia. Electronic address: amy.hutchi
Obesity and its associated metabolic disturbances, including insulin resistance, inflammation, hypertension, dyslipidemia, and plaque progression, are key drivers of cardiovascular risk. Established dietary strategies, such as the Mediterranean diet, Dietary Approaches to Stop Hypertension (DASH), and calorie restriction (CR), play a crucial role in preventing and slowing the progression of cardiovascular diseases (CVDs). Time-restricted eating (TRE) is a form of intermittent fasting where food intake is limited to 6-10 h daily, typically during daytime hours, and is showing potential to improve cardiovascular health.
View Article and Find Full Text PDFFront Nutr
August 2025
Faculty of Health Social Care and Medicine, Edge Hill University, Ormskirk, United Kingdom.
The increasing prevalence of type 2 diabetes mellitus (T2DM) has inspired researchers to investigate therapies and tools supporting the treatment of this disease. One such tool is intermittent fasting (IF). Given the nature and mechanism of action of IF, it would be logical for it to have a beneficial effect on T2DM patients.
View Article and Find Full Text PDFFront Public Health
August 2025
Department of Physical Activity and Health Promotion Science, Poznan University of Physical Education, Poznań, Poland.
Background: Cognitive complaints are commonly reported during menopause. Lifestyle interventions, such as exercise and time-restricted eating, are being investigated for their potential role in supporting cognitive health during menopause. This study investigated the effect of combining time-restricted eating (16:8) with a resistance and endurance circuit training program on cognitive health, as assessed using a comprehensive multi-domain cognitive test battery, in perimenopausal, menopausal, and postmenopausal women.
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