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http://dx.doi.org/10.1111/hepr.14235 | DOI Listing |
Clin Spine Surg
September 2025
Department of Neurosurgery, Neurosurgery, The Walton Centre NHS Foundation Trust, Lower Lane.
Study Design: Retrospective cohort study.
Objective: To characterise patients admitted to a UK tertiary centre with OPLL over a 10-year period.
Summary Of Background Data: OPLL is a progressive degenerative condition that can lead to myelopathy.
Food Sci Biotechnol
October 2025
School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, 310023 Zhejiang China.
Unlabelled: Lactose intolerance is defined as the inability to digest lactose due to insufficient activity of the β-galactosidase enzyme, which catalyzes the hydrolysis of lactose into glucose and galactose. This study evaluated the potential probiotic properties of isolated S8, which exhibiting high β-galactosidase activity. The strain demonstrated higher survival rate under gastrointestinal stress, with 80% and 63% viability after 3 h in simulated gastric fluid and 8 h in intestinal fluid, respectively, while retaining 60.
View Article and Find Full Text PDFJ Endocr Soc
October 2025
Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.
Although indicated as adjunctive therapy for seizure disorders, ketogenic diets (KDs) have gained popularity for weight loss and mitigating the metabolic risks associated with severe obesity. However, efficacy, durability, and long-term consequences are incompletely understood. In preclinical models, most studies have included only male mice, precluding an understanding of sex-specific responses to KD.
View Article and Find Full Text PDFJ Nutr Biochem
September 2025
Department of Woman-Mother-Child, Division of Pediatrics, DOHaD Laboratory, University of Lausanne and Lausanne University Hospital, 1011 Lausanne, Switzerland. Electronic address:
Background: Individuals born after intrauterine growth restriction (IUGR) have a higher risk of developing metabolic syndrome (MetS) in adulthood. In a rat model, male IUGR offspring exhibit MetS features-including elevated systolic blood pressure, glucose intolerance, non-alcoholic fatty liver disease, and increased visceral adipose tissue (VAT)-by 6 months of age. Female offspring, however, do not.
View Article and Find Full Text PDFReprod Biol
September 2025
Nanjing Women and Children's Healthcare Institute, Women's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, Nanjing, Jiangsu, China. Electronic address:
Gestational diabetes mellitus (GDM) is a common and serious complication during pregnancy. Depleted next-generation probiotic, Akkermansia muciniphila (AKK) in GDM women indicates its potential on GDM prevention. However, the functions and mechanisms of AKK on GDM remain unclear.
View Article and Find Full Text PDF