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JOURNAL/mgres/04.03/01612956-202603000-00001/figure1/v/2025-06-28T140100Z/r/image-tiff Avascular necrosis of the femoral head is a condition resulting from disrupted blood supply, leading to ischemia and bone tissue necrosis. Core decompression (CD) restores the blood supply through pressure relief, whereas hyperbaric oxygen (HBO) enhances tissue oxygenation and promotes bone repair. Their combined use may complement each other in improving blood supply, promoting bone healing, and inhibiting disease progression, thus achieving a better therapeutic effect. To assess and compare the efficacy of HBO and/or CD for treating mild to moderate femoral head avascular necrosis, a retrospective study was conducted on patients diagnosed with Ficat stage II non-traumatic osteonecrosis between January 2017 and January 2022 at the Affiliated Central Hospital of Shenyang Medical University, China. A total of 72 patients were divided into HBO, CD, and combination groups, with 24 patients in each group. After 1 year of follow-up, 90% of patients in the HBO group, 85% in the CD group, and 95% in the combination group showed satisfactory improvements in hip joint function. The SF-36 quality of life questionnaire scale scores also significantly improved in all three groups, with the combination group showing the most significant improvement. These findings suggest that HBO offers promising potential for treating non-traumatic femoral head necrosis, with efficacy similar to that of CD. The combination group showed the most significant improvement in both hip joint function and quality of life.
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http://dx.doi.org/10.4103/mgr.MEDGASRES-D-24-00162 | DOI Listing |
Med Eng Phys
October 2025
Centre for Simulation in Bioengineering, Biomechanics and Biomaterials (CS3B), Department of Mechanical Engineering, School of Engineering of Bauru, São Paulo State University (UNESP), Bauru, São Paulo, Brazil. Electronic address:
This study aimed to evaluate the near-cortical over-drilling technique on the mechanical behaviour of bone-plate constructs in a rabbit transverse femoral fracture. In vitro biomechanical testing and finite element (FE) models were used for analyses. Rabbits' bones (n = 14) were divided into two groups: G1 - without near-cortical over-drilling, and G2 - with near-cortical over-drilling.
View Article and Find Full Text PDFJ Am Acad Orthop Surg Glob Res Rev
September 2025
From the Mayo Clinic Alix School of Medicine, Scottsdale, AZ (Ms. Hiredesai and Mr. Holle), and the Department of Orthopedic Surgery, Mayo Clinic, Phoenix, AZ (Dr. Van Schuyver, Dr. Deckey, Dr. Probst, and Dr. Spangehl).
Atraumatic bilateral osteonecrosis of the femoral head (ONFH) is a rare phenomenon whose etiology is not fully understood. In this report, we describe the case of a 75-year-old female patient who developed rapidly onset bilateral ONFH after intra-articular corticosteroid injections. She was treated with staged bilateral total hip arthroplasty.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Department of Orthopedics and Traumatology, Brazilian Association for the Welfare of the Handicapped Children (AACD), São Paulo, SP, Brazil.
Hip dysplasia in cerebral palsy (CP) is a common and severe problem, especially among nonambulatory patients. A likely cause is muscular imbalance and developmental bone changes leading to a progressive extrusion of the femoral head from the acetabulum. The ideal surgical treatment aims to reduce the dislocated hip to improve pain, positioning, and function.
View Article and Find Full Text PDFJ Clin Orthop Trauma
November 2025
Department of Orthopaedics, PGIMS Rohtak, India.
Background: Total hip arthroplasty (THA) is a common intervention for severe hip disorders. However, postoperative instability and dislocation continue to present significant challenges. To address these issues, dual mobility (DM) cups and large femoral heads (LFH) have been employed, each offering unique biomechanical benefits.
View Article and Find Full Text PDFInjury
August 2025
Department of Trauma Surgery, University and University Hospital of Zurich, Raemistr. 100, 8091 Zurich, Switzerland; Center for Preclinical Development, University and University Hospital of Zurich, Raemistr. 100, 8091 Zurich, Switzerland. Electronic address:
Background: Critical size bone defects represent a clinical challenge, associated with considerable morbidity, and frequently trigger the requirement of secondary procedure. To fill osseous gaps, multiple steps are required, such as proliferation and differentiation on the cellular level and the building of extracellular matrix. In addition, the osteogenic potential of cell-derived extracellular matrices (CD-ECM) is known to enhance bone healing.
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