Cyclic Vomiting Syndrome as a Migraine Variant in Adults: A Case Report.

Pain Med Case Rep

Stanley H. Appel Department of Neurology, Houston Methodist Neurological Institute, Houston, TX.

Published: September 2024


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Article Abstract

Background: Cyclic vomiting syndrome (CVS) is a complex medical disorder characterized by debilitating attacks of nausea and vomiting lasting hours to days. CVS often acts as a migraine precursor or variant in the pediatric population, but its relationship with migraine in adults is not well established.

Case Report: Here, we report a case of adult-onset CVS with recurrent attacks of nausea, vomiting, and malaise for several years causing significant morbidity and work loss. Atypical migraine was suspected, and the disorder was controlled with effective antimigraine therapy.

Conclusions: Our study contributes to the increasing body of evidence that underscores CVS as a migraine variant. This recognition enhances our comprehension of CVS and guides the development of more efficacious treatment approaches.

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