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Background: Understanding what drives effective implementation is the key to making more sustainable developments. Blood and its components are critical for life-saving transfusions, however, their availability at the point of care is often limited. Moreover, the logistical challenges associated with blood product transport are substantial and maintaining the cold chain throughout the supply route is crucial to sustain their functional integrity as the temperature fluctuations can compromise its oxygen-carrying capacity. Furthermore, factors such as unpredictable demand, remote geographical locations, and extreme climatic conditions can further compound these difficulties. With India's diverse and distinct topographical variations and geographical spread, last-mile service deliveries of healthcare supplies face multiple challenges. Unmanned Aerial Vehicles (UAVs) or drones are emerging technologies with the potential to leapfrog the last mile logistics solution for transporting medical supplies thus, strengthening the overall healthcare system.
Methods: This study investigates the impact of drone-based delivery on the quality and stability of blood components, relative to conventional transport methods along with the operational challenges associated with implementing a drone-based blood delivery system. To achieve these objectives, the EPIS (Exploration, Preparation, Implementation, Sustainment) framework was adopted, which facilitates a systematic approach to this complex implementation process. The drone-related technical and logistic challenges encountered during the study were also identified.
Results: The study documents the challenges experienced by the study team during the drone-based delivery of blood while maintaining the biochemical parameters of blood components. During the drone based transportation the temperature, integrity of blood cells, and other parameters were maintained, while slight changes in few parameters were observed via both transportation modes. In this study the drone travelled around 36 km in 8 min, while van took around 55 min to cover the same distance.
Conclusions: The present study was done to assess the impact of drone-based delivery on the blood components after the transportation and their comparison to conventional modes of transportation, also, to lay foundation for the successful and sustainable drone-based blood delivery programs. This study suggests that the blood and its components can be transported safely by drone following standard guidelines, which could be helpful particularly in determining blood in emergency situation and difficult terrains.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12183833 | PMC |
http://dx.doi.org/10.1186/s13690-025-01650-z | DOI Listing |
Int J Gen Med
September 2025
Department of Dermatology, Hangzhou Third People's Hospital, Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, People's Republic of China.
Background: Nodular hidradenoma (NH) is a rare benign adnexal tumor originating from sweat glands, often misdiagnosed due to nonspecific clinical manifestations. Ultrasonography (US) plays a critical role in the diagnosis of skin tumors, yet systematic descriptions of its sonographic features remain limited.
Objective: This study aims to investigate the very-high-frequency (VHF) characteristics of eccrine nodular hidradenoma (ENH) and establish key imaging criteria to differentiate it from other cutaneous/subcutaneous lesions.
BMC Pediatr
September 2025
Department of Neonatology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China.
Background: Red blood cell (RBC) transfusion is a common intervention for anemia in preterm infants; however, its association with bronchopulmonary dysplasia (BPD) remains debated. While biological mechanisms suggest potential harm, the clinical impact of transfusion frequency on BPD incidence and severity remains unclear.
Objective: To investigate whether RBC transfusion frequency is independently associated with the risk and severity of BPD in preterm infants born before 32 weeks of gestation.
Acta Ortop Mex
September 2025
Servicio de Ortopedia y Traumatología, Hospital de San Rafael, Hospitales Pascual. Cádiz, España.
Introduction: anatomical deformities such as developmental dysplasia of the hip (DDH) and Perthes disease represent a challenge for reconstruction. The use of 3D-printed models can be helpful for assessing the deformity, bone mass, implant size, and orientation.
Objectives: to prospectively evaluate the outcomes of 3D simulation in primary total hip arthroplasty.
Nutr Metab Cardiovasc Dis
August 2025
Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Background And Aims: Although secondhand smoke (SHS) exposure has been linked with metabolic syndrome (MetS) in never-smokers, its effects among individuals who have quit smoking remain unclear. This study investigated the relationship between changes in SHS exposure and incident MetS in a large cohort of Korean former smokers.
Methods And Results: We analyzed 17,269 Korean former smokers without MetS at baseline from a longitudinal cohort, with a median follow-up of three years.
BMJ
September 2025
Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Objective: To determine the effect of a prepregnancy lifestyle intervention on glucose tolerance in people at higher risk of gestational diabetes mellitus.
Design: Single centre randomised controlled trial (BEFORE THE BEGINNING).
Setting: University hospital in Trondheim, Norway.