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Article Abstract

Background: Cerebral embolic protection devices (CEPDs) have been developed to decrease embolic brain injury and stroke during transcatheter aortic valve replacement (TAVR). Simplifying vascular access for a CEPD may increase procedural efficiency and safety FIRST-IN-HUMAN/EARLY REPORTS SUMMARY: This is the first published report of the use of the novel EnCompass F filter, which consists of a cylindrical nitinol frame and electrospun filter. Complete cerebral embolic protection during TAVR is possible through single femoral arterial access.

Discussion: Cerebral protection was feasible and safe without device-related complications, clinical stroke, or other neurologic events. Postprocedural diffusion-weighted magnetic resonance imaging revealed only 1 very small, clinically insignificant new brain lesion.

Novelty: This presents the first successful use of a CEPD in TAVR through access by a single femoral artery.

Take-home Message: The use of the novel EnCompass F filter was feasible to provide complete cerebral embolic protection in TAVR using a single access.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12198642PMC
http://dx.doi.org/10.1016/j.jaccas.2025.103768DOI Listing

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