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The position of the umbilical cord within the uterus is influenced by its insertion site, with low insertion near the internal os raising concerns regarding the risk of cord prolapse and feasibility of vaginal delivery. This report describes a case of persistent cord presentation caused by marginal cord insertion at the lower edge of a low-lying placenta, further complicated by preterm premature rupture of membranes (pPROM) at 30 weeks. Given the fetal immaturity, expectant management was pursued despite the potential risk of cord prolapse. Although persistent amniotic fluid leakage occurred, no signs of fetal compromise or immediate cervical ripening were noted. Sequential transvaginal ultrasound examinations over a period of more than one month demonstrated a gradual resolution of cord presentation, likely facilitated by placental migration and descent of the fetal head shortly before the onset of labor. This progression ultimately enabled successful vaginal delivery at 35 weeks. The case reported herein highlights the critical role of close monitoring in managing persistent cord presentation associated with low cord insertion. Our findings suggest the possibility of avoiding cesarean delivery in similar high-risk scenarios.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178148 | PMC |
http://dx.doi.org/10.7759/cureus.84467 | DOI Listing |
Pain Med Case Rep
December 2023
Beth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care, and Pain Medicine, Harvard Medical School, Boston, MA.
Background: Spinal cord stimulation (SCS) is a minimally invasive neuromodulation treatment modality primarily used for failed back surgery syndrome (FBSS), complex regional pain syndrome, and diabetic neuropathy. Specifically, when utilized for the treatment of FBSS, placement can be complicated by the excessive scarring, adhesions, and altered anatomy limiting the access to the epidural space and advancement of the leads.
Case Report: Our patient is a 58-year-old woman with a history of scoliosis and severe lumbar spinal stenosis who presented for trial of an SCS for FBSS.
Pain Med Case Rep
December 2023
Department of Anesthesia and Critical Care Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA.
Background: Immunosuppression after cervical epidural steroid injection (CESI) is a potential complication. This report discusses the development of an aortoesophageal fistula following a CESI.
Case Report: Patient is a man in his early 60s with a history of central spinal cord syndrome status post (s/p) anterior cervical discectomy and fusion of C3-C6 and thoracic aortic aneurysm s/p thoracic endovascular aortic repair (TEVAR) who presented with cervical radiculopathy.
Pain Med Case Rep
November 2023
Beth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care, and Pain Medicine, Harvard Medical School, Boston, MA.
Background: Spinal cord stimulation (SCS) is a minimally invasive neuromodulation treatment modality primarily indicated for failed back surgery syndrome (FBSS). When FBSS occurs in the setting of spinal cord injury (SCI) it can often be refractory to treatment with opioids and anticonvulsants; in such cases, SCS has demonstrated promising results. Here, we present a case series of 2 patients with FBSS in the setting of SCI who received pain relief with SCS therapy.
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September 2023
Baylor College of Medicine, H. Ben Taub Department of Physical Medicine and Rehabilitation, Houston, TX.
Background: Cluneal neuralgia is increasingly becoming recognized as an etiology of low back pain. The majority of the literature on cluneal nerve interventions describes modalities targeting the superior cluneal nerves with little emphasis on the middle cluneal nerves.
Case Report: A 21-year-old woman with a medical history of congenital myelomeningocele with tethered cord at L5-S1, status post 3 decompressive releases, presented to the clinic with chronic low back pain and associated sacroiliac paresthesia.
FASEB J
September 2025
Department of Plastic Surgery and Burn, Third XiangYa Hospital, Central South University, Changsha, Hunan, China.
Defective wounds pose health risks, and treatment is challenging. Umbilical cord-derived mesenchymal stem cells (UCMSCs) show promise for healing. Primary UCMSCs were isolated and extracted in vitro, and the proliferation and differentiation characteristics were detected by flow cytometry and trilineage differentiation, and a 3D spherical cell culture was performed.
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