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Article Abstract
is the main spoilage fungus that causes the deterioration of paocai. Our previous study found that the compound essential oils (CEOs) of lemon, lemongrass, and nutmeg had a good inhibitory effect; however, the antimicrobial mechanism was unknown. In order to elucidate the mechanism of action of the CEO in inhibiting , transcriptomics and metabolomics were used for joint analysis. The results showed that the minimum inhibitory concentration (MIC) of was 2 µL/mL, and the combined multi omics analyses indicated that the treatment of the CEO disrupted the ABC transporters, glycophospholipid metabolism, and nucleotide metabolism of , leading to the disruption of the integrity of cell wall and cell membrane, resulting in energy and metabolic dysfunction, and ultimately achieving the effect of inhibiting . The results of this study provided new insights into the mechanism of inhibition by CEOs, and provide a reference basis for the development of food-related bacteriostatic agents by CEOs.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12155328 | PMC |
| http://dx.doi.org/10.3390/foods14111998 | DOI Listing |
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