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http://dx.doi.org/10.1200/OP-25-00064 | DOI Listing |
Methods Cell Biol
September 2025
Histology and Cell Biology Department, School of Medicine, Complutense University of Madrid, Madrid, Spain. Electronic address:
Parkinson disease (PD) is the second most prevalent neurodegenerative disorder globally, trailing only Alzheimer´s disease. It currently affects nearly 3 % of individuals aged 65 and above. The disease is characterized by the progressive loss of dopaminergic neurons accompanied by a chronic neuroinflammatory process, which is responsible for both motor symptoms (tremor, rigidity, bradykinesia) and non-motor symptoms (depression, dysphagia, anxiety, constipation, and anosmia).
View Article and Find Full Text PDFChem Soc Rev
September 2025
State Key Laboratory of Crystal Materials, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China.
Understanding the excited-state dynamics of atomically precise coinage metal nanoclusters (CMNCs) is pivotal for elucidating their photoluminescence (PL) mechanisms and rationally tuning emission properties-particularly in the near-infrared (NIR) region, where CMNC-based nanomaterials have tremendous potential for biomedical and optoelectronic applications. This review presents a systematic and comprehensive account of recent advances in investigating the excited-state dynamics and PL mechanisms of NIR-emitting CMNCs with atomic precision, leveraging the synergistic integration of time-resolved spectroscopy and time-dependent density functional theory (TD-DFT) calculations. Distinct from previous reviews that offer a broad survey of CMNC properties, the present review focuses specifically on intrinsic factors, highlighting molecular vibrational features and electronic structure modulation as key determinants of NIR emission.
View Article and Find Full Text PDFJ Histotechnol
September 2025
Department of Pathology, Peking University Third Hospital, Beijing, China.
Amyloidosis encompasses a spectrum of rare disorders characterized by extracellular amyloid deposition. Achieving an accurate early diagnosis of systemic amyloidosis necessitates biopsy-specific pathological evaluation. Formalin-fixed, paraffin-embedded liver biopsy specimens were examined using Congo red staining, electron microscopy, immunohistochemistry (IHC), immunofluorescence, and Congo red-assisted laser microdissection with mass spectrometry (LMD/MS).
View Article and Find Full Text PDFComput Methods Programs Biomed
August 2025
Zhengzhou University, School of Computer and Artificial Intelligence, Zhengzhou, 450001, China. Electronic address:
Background And Objective: The early detection of breast cancer plays a critical role in improving survival rates and facilitating precise medical interventions. Therefore, the automated identification of breast abnormalities becomes paramount, significantly enhancing the prospects of successful treatment outcomes. To address this imperative, our research leverages multiple modalities such as MRI, CT, and mammography to detect and screen for breast cancer.
View Article and Find Full Text PDFPLoS One
September 2025
School of Emergency Technology, Guangzhou Vocational College of Technology and Business, Guangzhou, China.
Under China's national sustainability strategy, the logistics industry is confronted with the imperative of high-quality green development. Given its status as the leading economic province and a national logistics hub, investigating green logistics development in Guangdong province holds paramount strategic importance. To comprehensively evaluate green logistics development efficiency of 21 cities in Guangdong from 2016 to 2022, this study employed the super-efficiency slacks-based measure model (Super-SBM) with undesirable outputs, the Global Malmquist-Luenberger (GML) productivity index and a four-quadrant analysis based on static and dynamic efficiency.
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