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Fully wearable devices are crucial for real-time health monitoring, but existing devices often lack stable power, on-site signal processing, and multimodal sensing. To overcome these limitations, we introduce the first self-powered and fully wearable sensor (MESFW) based on multiplexed green biofuels. The MESFW integrates a microfluidic module, sensing module, laser-induced graphene (LIG) electrodes, and customized electronics, enabling highly sensitive detection of glucose and alcohol in noninvasive biofluids (sweat, breath, saliva, tears) while monitoring daily activities (temperature, pressure, touch). Experiments show the MESFW can track glucose and alcohol levels before and after meals/drinking, powered continuously for 24 h. With machine learning, it accurately identifies wearing types and enables real-time health prediction. This innovation offers a novel approach to real-time physiological monitoring.
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http://dx.doi.org/10.1021/acs.nanolett.5c02380 | DOI Listing |
Nanomicro Lett
September 2025
Nanomaterials & System Lab, Major of Mechatronics Engineering, Faculty of Applied Energy System, Jeju National University, Jeju, 63243, Republic of Korea.
Wearable sensors integrated with deep learning techniques have the potential to revolutionize seamless human-machine interfaces for real-time health monitoring, clinical diagnosis, and robotic applications. Nevertheless, it remains a critical challenge to simultaneously achieve desirable mechanical and electrical performance along with biocompatibility, adhesion, self-healing, and environmental robustness with excellent sensing metrics. Herein, we report a multifunctional, anti-freezing, self-adhesive, and self-healable organogel pressure sensor composed of cobalt nanoparticle encapsulated nitrogen-doped carbon nanotubes (CoN CNT) embedded in a polyvinyl alcohol-gelatin (PVA/GLE) matrix.
View Article and Find Full Text PDFProg Mol Biol Transl Sci
September 2025
Department of Systems and Computer Engineering, Carleton University, Ottawa, ON, Canada. Electronic address:
Monitoring skeletal muscle contraction provides valuable information about the muscle mechanical properties, which can be helpful in various biomedical applications. This chapter presents a single-element flexible and wearable ultrasonic sensor (WUS) developed by our research group and its application for continuously monitoring and characterizing skeletal muscle contraction. The WUS is made from a 110-µm thick polyvinylidene fluoride piezoelectric polymer film.
View Article and Find Full Text PDFAPL Bioeng
September 2025
The BioRobotics Institute and Department of Excellence in Robotics & AI, Scuola Superiore Sant'Anna, Pisa, Italy.
A fully implantable sensorized organ to replace the natural urinary bladder holds considerable promise for patients undergoing radical cystectomy. Clinical options to restore continence include urine redirection to wearable bags or reconstruction of neobladders from autologous tissues, often with limited capacity. However, none of these approaches can restore patient's ability to perceive bladder fullness, making voiding self-management complex and burdensome.
View Article and Find Full Text PDFMicromachines (Basel)
August 2025
Department of Biomedical Engineering, University of Calgary, Calgary, AB T2N 1N4, Canada.
Microneedles have emerged as a versatile technology for biosensing across biomedical domains and are increasingly being explored for other applications like agriculture. This review highlights recent advancements in the development of microneedle-based biosensors in novel areas. Biomedical applications include continuous glucose monitoring, multiplexed biomarker detection beyond glucose, and numerous recent works presenting fully integrated systems comprising microneedle arrays alongside miniaturized wearable electronics.
View Article and Find Full Text PDFSensors (Basel)
August 2025
Institute of Rehabilitation Engineering and Technology, University of Shanghai for Science and Technology, Shanghai 200093, China.
A wearable closed-loop transcutaneous electrical nerve stimulation (TENS) platform has been developed to address the limitations of conventional open-loop neuromodulation systems. Unlike existing systems such as CLoSES-which targets intracranial stimulation-and electromyography-triggered functional electrical stimulation (EMG-FES) platforms primarily used for motor rehabilitation, the proposed device uniquely integrates low-latency surface electromyography (sEMG)-driven control with six-channel current stimulation in a fully wearable, non-invasive format aimed at ambulatory pain modulation. The system combines real-time sEMG acquisition, adaptive signal processing, a programmable multi-channel stimulation engine, and a high-voltage, boost-regulated power supply within a compact, battery-powered architecture.
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