Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
The development of novel topologies in covalent organic frameworks (COFs) enhances reticular chemistry and materials science, offering a systematic approach to constructing COFs and uncovering intricate relationships between their structures and properties. The inclusion of aminal derived linkages enables COFs with greater structural diversity and exceptional functionalities. This study examines the graph-structural properties of aminal-linked COFs using entropy information and hybrid topological descriptors, determining their topological complexity. Additionally, we employ these descriptors as the basis for robust statistical regression models, facilitating the generation of graph energies for these frameworks and the analysis of HOMO-LUMO gaps.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12141726 | PMC |
| http://dx.doi.org/10.1038/s41598-025-01210-z | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
High Capacity and Efficient Adsorption of Lutetium(III) by the Metal-Organic Framework HKUST-1 in Simulated Medical Wastewater.
Ann N Y Acad Sci
September 2025
School of Nuclear Science and Technology, University of South China, Hengyang, China.
Lutetium (Lu(III)), a heavy rare earth element, plays a critical role in advanced industrial processes and nuclear medicine applications. Given its high economic value and potential environmental risks, the recovery of Lu(III) from medical wastewater is both necessary and urgent. However, previous studies on the adsorption behavior of Lu(III) have been limited by low adsorption capacity, competition from coexisting metal ions, and the influence of environmental temperature.
View Article and Find Full Text PDFA novel molecularly imprinted 3D COF-based magnetic solid-phase extraction combined with UHPLC-MS/MS to detect trace residues of acyclovir, penciclovir and ganciclovir in animal-derived food.
Food Chem
September 2025
Shanghai Frontiers Science Center of Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy, Engineering Research Center of Cell & Therapeutic Antibody, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address:
The residues of antiviral drugs acyclovir (ACV), penciclovir (PCV) and ganciclovir (GCV) in foods, particularly in ready-to-eat products, pose a significant threat to human health, making it urgent to develop a rapid and sensitive method for their detection. Herein, we designed a novel magnetic molecularly imprinted three-dimensional covalent organic framework (MICOF@FeO) for selective extraction of these antiviral drugs from complicated food matrix. The prepared MICOF@FeO integrates molecular recognition ability, 3D COF structural advantages and magnetic responsiveness, providing high selectivity, large adsorption capacity and facile operation for magnetic solid-phase extraction (MSPE).
View Article and Find Full Text PDFUltrafast Correlation Energy Estimator.
J Phys Chem A
September 2025
Institute of Physics, Faculty of Physics, Astronomy, and Informatics, Nicolaus Copernicus University in Toruń, ul. Grudzia̧dzka 5, 87-100 Toruń, Poland.
A virtually no-cost method is proposed that can compute the correlation energies of general, covalently bonded, organic, and inorganic molecules (including conjugated π-electron systems) with a well-defined dominant Lewis structure at the accuracy of 99.5% of the near-exact values determined by the coupled-cluster singles, doubles, and perturbative triples [CCSD(T)] in the complete-basis-set (CBS) limit. This Correlation Energy Per Bond (CEPB) method assigns a partial correlation energy to each bond type (characterized by the identities of the two atoms forming the bond and its integer bond order) and to a lone pair, regardless of the bond length, bond angle, sp-hybridization, π-electron conjugation, ionicity, noncovalent interactions, etc.
View Article and Find Full Text PDFAn Activatable and Covalent Tumor-Associated Antigen Capturer Enabling Systemic Injection for Promoted Antitumor Immunity.
J Am Chem Soc
September 2025
Frontiers Science Center for New Organic Matter, State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and Academy for Advanced Interdisciplinary Studies, Nankai University, Tianjin 300071, PR China.
Antigen-capturing nanomaterials hold great promise for cancer immunotherapy; however, the need for tumor localized administration and limited antigen-binding affinity remains the "Achilles heel" of this strategy. Herein, we present a tumor microenvironment (TME)-activatable nanoplatform, TDR848@FPB, designed for systemic administration and enhanced covalent capture of tumor-associated antigens (TAAs), enabling effective immunotherapy with minimal off-target effects and independent of localized tumor administration. This platform encapsulates a photosensitizer-conjugated, light-activated toll-like receptor (TLR) agonist, which induces immunogenic cell death and triggers a pro-inflammatory TME conducive to antigen capture upon light irradiation.
View Article and Find Full Text PDFConstruction of Hollow Structured Covalent Organic Framework with Chiral Internal Catalytic Sites for Asymmetric Hydrogenation.
Small
September 2025
College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan, 250014, P. R. China.
The functionality of covalent organic frameworks (COFs) is usually highly related to their morphologies. Among various morphologies, the hollow-structured COFs have recently attracted intense attention due to their unique properties. Herein, the synthesis of hollow structured COFs are first reported with the chiral internal sites via combining the chiral templating method with the acid etching approach.
View Article and Find Full Text PDF