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Introduction Accurate selection of gingival formers is critical for achieving optimal peri-implant soft tissue health and esthetics. Crestal mucosal thickness may play a significant role in the success of gingival former selection, particularly in single-tooth implant prosthodontics. The present study aimed to evaluate the impact of crestal mucosal thickness on the accuracy of gingival former selection using retrospective clinical data and cone-beam computed tomography (CBCT) analysis. Materials and methods This retrospective, cross-sectional, observational study was conducted in the Department of Prosthodontics after obtaining ethical approval. Patient records of 150 implant sites from August 2021 to December 2024 were reviewed. The inclusion criteria were adults (18-65 years) with single-tooth implants, adequate periodontal health, and complete clinical documentation, including CBCT scans. Patients with systemic conditions, tobacco use, or incomplete medical records were excluded. CBCT images were used to measure crestal mucosal thickness. The gingival former type, diameter, and clinical outcomes were documented. Accuracy of gingival former selection was defined as the absence of inflammation, ulceration, or recession, along with a good emergence profile at the final prosthetic placement. Statistical analyses included chi-square tests, independent t-tests, and multivariate logistic regression. Results Of the 150 implant sites, 108 (72%) had accurate gingival former selection, while 42 (28%) showed complications. No significant associations were found for sex (p = 0.894), jaw (p = 0.860), or site (p = 0.138). However, mucosal thickness significantly influenced selection accuracy (p = 0.001), with inaccurate outcomes more common in sites with <2 mm thickness. Accurate selections had significantly thicker mucosa (mean = 2.43 ± 0.3 mm) and smaller gingival formers (mean diameter = 4.45 ± 0.74 mm). Logistic regression revealed that thinner mucosa (odds ratio = 13.92) and larger former diameter (odds ratio = 4.15) were independent predictors of inaccurate selection. Conclusion Crestal mucosal thickness is a critical determinant for the accurate selection of gingival formers. Thin soft tissue biotypes and inaccurate formers significantly increase the risk of peri-implant soft tissue complications. Preoperative CBCT assessment and a tissue-informed approach are essential for optimizing outcomes in implant prosthodontics.
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http://dx.doi.org/10.7759/cureus.83477 | DOI Listing |
Am J Clin Pathol
September 2025
Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Objective: Choline transporter (ChT) immunohistochemistry (IHC) is a new ancillary test that aids in the diagnosis of Hirschsprung disease in newborns and infants. The behavior of this stain in older children (greater than 1 year of age) with chronic constipation, where Hirschsprung disease is clinically unlikely, has not been investigated. The aim of our study was to determine the behavior of ChT IHC in rectal biopsies performed on older children with chronic constipation.
View Article and Find Full Text PDFLasers Med Sci
September 2025
Department of Otolaryngology Head and Neck Surgery, BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, 71 Hexi Street, Nanjing 210019, Jiangsu, China.
To evaluated the efficacy of photodynamic therapy (PDT) in improving laryngeal mucosal wound scar healing in vivo and investigated its underlying mechanisms. Laryngeal mucosal wounds were induced in Sprague-Dawley rats. Two weeks post-injury, PDT was administered via intraperitoneal injection of 100 mg/kg 5-aminolevulinic acid (5-ALA) and 635-nm red laser irradiation at varying energy doses (15, 30, and 45 J/cm²).
View Article and Find Full Text PDFRhinology
September 2025
School of Medicine, Chang Gung University, Taoyuan, Taiwan.
Background: This study aimed to evaluate the presence of Serpentine Signs on computed tomography (CT) images and its impact on the clinical symptoms in patients with empty nose syndrome (ENS).
Methods: A retrospective study analysed patients with ENS enrolled in previous studies. The clinical characteristics and results of ENS-specific questionnaire evaluations were reviewed.
Surg Endosc
September 2025
Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Background And Aims: Traditional endoscopic full-thickness resection (EFTR) involves complete removal of the lesion followed by defect closure. The separated resection and closure technique results in mucosal eversion and misalignment of the muscularis propria layers, making reliable closure difficult. Here, we developed an innovative "cut-and-seal-as-you-go" technique, "Zipper-EFTR" and evaluated the feasibility and safety of the new technique.
View Article and Find Full Text PDFHistopathology
September 2025
Department of Pathology, University of Chicago Medicine, Chicago, Illinois, USA.
Collagenous gastritis (CG) is a rare gastrointestinal disorder characterized by subepithelial collagen deposition and lamina propria inflammation. Despite its first description over four decades ago, the pathogenesis remains unclear, with no standardized pathologic criteria/classification, treatment or established prognosis. A systematic PubMed search identified all English-language case reports, series and observational studies describing CG.
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