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http://dx.doi.org/10.1016/j.bneo.2024.100063 | DOI Listing |
Medicine (Baltimore)
September 2025
Division of General Internal Medicine, Department of Medicine, University Hospitals, Genève, Switzerland.
Rationale: This case highlights the importance of considering a wide range of possible diagnoses when faced with unexplained hemorrhagic symptoms. When standard investigations fail to identify a clear cause, it is essential to conduct a detailed dietary history. This can lead to the diagnosis of scurvy, a reversible vitamin C deficiency that is often overlooked in populations at risk.
View Article and Find Full Text PDFBlood
September 2025
University, Hospital and Faculty of Medicine, Hradec Králové, Czech Republic, Hradec Králové, Czech Republic.
Epcoritamab is a subcutaneous CD3xCD20 bispecific antibody approved as monotherapy for relapsed/refractory (R/R) follicular lymphoma (FL). We evaluated fixed-duration epcoritamab with rituximab plus lenalidomide (R2) in R/R FL in arm 2 of EPCORE® NHL-2 (phase 1b/2; NCT04663347). Patients received epcoritamab (2 step-up doses, then 48-mg full doses) for up to 2 years and R2 for up to 12 cycles (28 days/cycle).
View Article and Find Full Text PDFCell Mol Biol (Noisy-le-grand)
September 2025
Arencibia Clinic, San Sebastian, Spain.
Follicular unit extraction (FUE) has become a leading technique in hair transplantation, yet optimal management of the donor area remains a clinical challenge. This systematic review analyzes intraoperative and postoperative interventions applied to the donor area in FUE hair transplantation, with a focus on both clinical outcomes and the cellular and molecular mechanisms involved in tissue repair, inflammatory response, and regenerative processes. A comprehensive literature search was conducted in PubMed and EMBASE (January 2000-June 2025), identifying clinical studies that evaluated donor area treatments and reported outcomes related to healing, inflammation, infection, and patient satisfaction.
View Article and Find Full Text PDFInt J Vitam Nutr Res
August 2025
Department of Plastic and Cosmetic Center, The First Affiliated Hospital, Zhejiang University, 310003 Hangzhou, Zhejiang, China.
The vitamin B complex, a group of water-soluble vitamins, is essential for various metabolic and cellular processes and critical for achieving optimal surgical outcomes in plastic and cosmetic procedures. This review examines the mechanistic contributions of this complex at the cellular level, including any roles in mitochondrial bioenergetics, redox balance, gene regulation, and cellular repair mechanisms. Niacinamide, as a precursor to NAD⁺, enhances mitochondrial efficiency and facilitates energy production, supporting tissue regeneration.
View Article and Find Full Text PDFInt Immunol
September 2025
Department of Immunology, Graduate School of Medicine, Kyoto University.
B cells play a critical role in tumor immunity, with their presence associated with improved prognosis in various cancers, including endometrial cancer (EC). However, the nature of the B cell response within the tumor microenvironment (TME) remains incompletely understood. In this study, we conducted single-cell analyses of B cells and CD4+ T cells in the TME of EC.
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