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http://dx.doi.org/10.1016/j.jscai.2025.102565 | DOI Listing |
J Infect Dev Ctries
August 2025
Gastroenterology Division, Internal Medicine Department, Sultan Qaboos Comprehensive Cancer and Research Center (SQCCCRC), University Medical City (UMC), Muscat, Sultanate of Oman.
Introduction: Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) reactivation are known complications in immunocompromised hosts, particularly transplant recipients. However, their occurrence and clinical implications in patients with solid tumors remain underexplored. The introduction of immune checkpoint inhibitors (ICIs) has transformed cancer therapy, but immune-related adverse events (irAEs), including colitis, are increasingly recognized.
View Article and Find Full Text PDFArch Dis Child Fetal Neonatal Ed
September 2025
Department of Pediatrics, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Objective: Bronchopulmonary dysplasia (BPD) associated pulmonary hypertension (BPD-PH) is the most severe endotype of BPD; there is insufficient evidence to support the optimal screening strategy in at-risk infants. We hypothesised that serial echocardiography throughout hospitalisation would improve PH detection with increased negative predictive value (NPV) beyond 36 week's postmenstrual age (PMA).
Study Design: This was a single centre cohort study conducted between 2017 and 2023.
Inflamm Res
September 2025
Department of Trauma Surgery, Emergency Surgery and Surgical Critical, Tongji Trauma Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Background: Severe polytrauma is one of the leading causes of death and disability worldwide. Hyperferritinemia is increasingly recognized as a biomarker of critical illness, yet its prognostic significance in polytrauma remains underexplored. This multicenter study investigates the temporal dynamics of serum ferritin in polytrauma patients and its association with systemic inflammation, organ dysfunction, and mortality.
View Article and Find Full Text PDFBMJ Open Respir Res
September 2025
Division of Pulmonary and Allergy, Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea
Objective: This study aimed to evaluate the impact of serial bronchitic status over two consecutive years on clinical outcomes, including frequency of exacerbation and lung function decline rate.
Methods: We analysed data from 1265 participants enrolled in the Korea COPD Subgroup Study, a nationwide prospective observational chronic obstructive pulmonary disease (COPD) cohort. Bronchitic status was determined using subquestionnaires of the COPD Assessment Test at baseline and after 1 year, classifying patients into three serial bronchitic groups of persistently not bronchitic (NB), intermittently bronchitic (IB) and chronic bronchitis (CB).
J Adv Pharm Technol Res
August 2025
Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Indonesia.
is an ornamental plant known for its therapeutic properties, particularly its antimicrobial activity. This study attempted to identify bioactive compounds in the leaf extract and assess their antibacterial and antifungal efficacy against and , which are key contributors to early childhood caries (ECC). leaves were extracted using the maceration technique with 70% methanol.
View Article and Find Full Text PDF