98%
921
2 minutes
20
As a researcher and a physician working together to combat amyotrophic lateral sclerosis (ALS), we are acutely aware of both the urgent need for innovation and the persistent divide between laboratory discoveries and clinical care [...].
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12110534 | PMC |
http://dx.doi.org/10.3390/cells14100715 | DOI Listing |
ACS Nano
September 2025
Eastern Institute for Advanced Study, Eastern Institute of Technology, Ningbo, Zhejiang 315200, P. R. China.
Ni-Fe (oxy)hydroxides are among the most active oxygen evolution reaction (OER) catalysts in alkaline media. However, achieving precise control over local asymmetric Fe-O-Ni active sites in Ni-Fe oxyhydroxides for key oxygenated intermediates' adsorption steric configuration regulation of the OER is still challenging. Herein, we report a two-step dealloying strategy to fabricate asymmetric Fe-O-Ni pair sites in the shell of NiOOH@FeOOH/NiOOH heterostructures from NiFe Prussian blue analogue (PBA) nanocubes, involving anion exchange and structure reconstruction.
View Article and Find Full Text PDFJMIR Res Protoc
September 2025
University of Nevada, Las Vegas, Las Vegas, NV, United States.
Background: In-hospital cardiac arrest (IHCA) remains a public health conundrum with high morbidity and mortality rates. While early identification of high-risk patients could enable preventive interventions and improve survival, evidence on the effectiveness of current prediction methods remains inconclusive. Limited research exists on patients' prearrest pathophysiological status and predictive and prognostic factors of IHCA, highlighting the need for a comprehensive synthesis of predictive methodologies.
View Article and Find Full Text PDFACS Nano
September 2025
International School of Microelectronics, Dongguan University of Technology, Dongguan 523808, China.
Mimicking human brain functionalities with neuromorphic devices represents a pivotal breakthrough in developing bioinspired electronic systems. The human somatosensory system provides critical environmental information and facilitates responses to harmful stimuli, endowing us with good adaptive capabilities. However, current sensing technologies often struggle with insufficient sensitivity, dynamic response, and integration challenges.
View Article and Find Full Text PDFJCO Glob Oncol
May 2025
Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
Purpose: Breast cancer remains a significant public health challenge globally, as well as in India, where it is the most frequently diagnosed cancer in females. Significant disparities in incidence, mortality, and access to health care across India's sociodemographically diverse population highlight the need for increased awareness, policy reform, and research.
Design: This review consolidates data from national cancer registries, global cancer databases, and institutional findings from a tertiary care center to examine the epidemiology, clinical challenges, and management gaps specific to India.
Crit Care Explor
September 2025
Division of Tropical Medicine and Infectious Diseases, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Importance: Sepsis remains a leading cause of death in infectious cases. The heterogeneity of immune responses is a major challenge in the management and prognostication of patients with sepsis. Identifying distinct immune response subphenotypes using parsimonious classifiers may improve outcome prediction, particularly in resource-limited settings.
View Article and Find Full Text PDF