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Background: The global burden of diet-related chronic diseases and their future projections remain unclear. To address this gap, we present the latest data on deaths and disability-adjusted life years attributable to dietary factors from 1990 to 2021, focusing on noncommunicable diseases worldwide. Additionally, we provide predictions of mortality rates across different age groups through 2030.
Methods: Data from the Global Burden of Disease Study 2021 were analyzed to evaluate correlations between dietary factors and trends in chronic disease burden over a 30-year period. Moreover, we predicted the burden of chronic dietary diseases up to 2030.
Results: From 1990 to 2021, global age-standardized mortality rates and disability-adjusted life year (DALY) rates associated with dietary factors decreased by approximately one-third for neoplasms and cardiovascular diseases (CVDs). In high sociodemographic index (SDI) regions, neoplasm-related deaths showed a stronger correlation with dietary factors, particularly high red meat intake. In cardiovascular diseases, the leading dietary factors are low-grain diets, whereas in diabetes, it is due to increased intake of processed meat. In low-SDI regions, diets low in vegetables showed the strongest association with neoplasm-related mortality, while diets low in fruits were significantly linked to CVD and diabetes burden. High-sodium diet was a significant risk factor for CVD in the middle-SDI regions. Moreover, the 2030 projections indicated a decline in mortality from neoplasms and CVDs, with a slight increase in mortality rates from diabetes.
Conclusion: The global burden of chronic diseases linked to dietary factors shows varying trends across different countries and regions, particularly influenced by their economic development levels. This variation underscores the necessity of enhancing dietary structures to mitigate chronic disease prevalence and foster overall health.
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http://dx.doi.org/10.3389/fnut.2025.1570321 | DOI Listing |
Crit Rev Food Sci Nutr
September 2025
Food Safety Key Laboratory of Zhejiang Province, School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, China.
The prevalence of inflammatory bowel disease (IBD), including crohn's disease and ulcerative colitis, is rising worldwide. Among various potential contributors, low dietary fiber (DF) diet habit stands out as a substantial factor in this accelerating trend. Conversely, DF supplementation inhibits the manifestation of IBD pathology and promotes inflammatory remission.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Medicine, Al-Quds University, Jerusalem, Palestine.
Background: Undernutrition remains a persistent public health concern among young children in Palestine, shaped by a range of socioeconomic and dietary factors. This study applies a Structural Equation Modeling (SEM) approach to explore both direct and indirect determinants of child growth among children aged 6-59 months in the West Bank.
Methods: Data were drawn from a 2022 cross-sectional survey involving 300 children selected from 1,400 households.
Crit Rev Food Sci Nutr
September 2025
Hunan Key Laboratory of Deep Processing and Quality Control of Cereals and Oils, State Key Laboratory of Utilization of Woody Oil Resource, College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan, China.
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a condition that results from metabolic disorders. In addition to genetic factors, irregular and high-energy diets may also significantly contribute to its pathogenesis. Dietary habits can profoundly alter the composition of gut microbiota and metabolites.
View Article and Find Full Text PDFEnviron Sci Technol
September 2025
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
While the cancer genome is well-studied, the nongenetic exposome of cancer remains elusive, particularly for regionally prevalent cancers with poor prognosis. Here, by employing a combined knowledge- and data-driven strategy, we profile the chemical exposome of plasma from 53 healthy controls, 14 esophagitis and 101 esophageal squamous cell carcinoma (ESCC) patients, and 46 esophageal tissues across 12 Chinese provinces, integrating inorganic, endogenous, and exogenous chemicals. We first show that components of the ESCC chemical exposome mediate the relationship between ESCC-related dietary/lifestyle factors and clinic health status indicators.
View Article and Find Full Text PDFNutr Health
September 2025
Department of Nursing, Faculty of Health Sciences, John Paul II University in Biała Podlaska, Biala Podlaska, Poland.
Healthy plant-based diets, such as vegan and vegetarian diets, as well as planetary health diets, meet the recommendations of sustainable dietary patterns and are healthier for both the planet and humans. The adoption of these dietary patterns may depend on socio-demographic factors and individual motivations. This study aimed to analyse the association between socio-demographic factors and knowledge and attitudes towards vegan and vegetarian diets amongst university students.
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