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The cumulative evolution of technology has proven central to our species' ecological success, allowing for cultural rather than biological adaptation to environmental challenges. While cumulative improvement explains how specific technological traditions can get increasingly better at solving pre-existing adaptive problems, it remains fundamentally an optimization process, one which halts when an optimal solution is found. Yet, humans are also capable of open-ended or evolvable technological change, that is, we have the capacity for generating novel and useful technological solutions for an ever-expanding set of increasingly complex problems. How novel problems of increasing complexity are accessed, however, remains an open issue. Here, I argue that human open-ended technological evolution emerges from the cultural evolutionary bootstrapping of our inventive capabilities through cognitive technologies. By inventing technologies that enhance our cognitive capabilities, we become able to invent technologies that would have been impossible to design using only our core (noncultural) cognitive abilities. These inventions include further empowering cognitive technologies, creating a feedback loop through which inventors become increasingly capable of making themselves even more capable inventors. I propose a model for how the cultural evolution of increasingly sophisticated cognitive technologies enables access to previously unreachable invention problems, driving open-ended technological change. This process differs from cumulative optimization as it involves expanding the range of problems that can be solved (evolvability) rather than optimizing solutions to existing problems (adaptation). This paper contributes to our understanding of human technological uniqueness by identifying a mechanism enabling open-ended cultural evolution.
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http://dx.doi.org/10.1111/tops.70012 | DOI Listing |
Alzheimers Dement
September 2025
Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, South Korea.
Introduction: We developed and validated age-related amyloid beta (Aβ) positron emission tomography (PET) trajectories using a statistical model in cognitively unimpaired (CU) individuals.
Methods: We analyzed 849 CU Korean and 521 CU non-Hispanic White (NHW) participants after propensity score matching. Aβ PET trajectories were modeled using the generalized additive model for location, scale, and shape (GAMLSS) based on baseline data and validated with longitudinal data.
Stroke
September 2025
Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, China (H.Z., K.H., Q.G.).
Background: Poststroke cognitive impairment (PSCI) affects 30% to 50% of stroke survivors, severely impacting functional outcomes and quality of life. This study uses functional near-infrared spectroscopy (fNIRS) to assess task-evoked brain activation and its potential for stratifying the severity in patients with PSCI.
Method: A cross-sectional study was conducted at Nanchong Central Hospital between June 2023 and April 2024.
Glob Ment Health (Camb)
July 2025
School of Social Sciences, College of Humanities, Arts, and Social Sciences, Nanyang Technological University, Singapore.
The global prevalence of mental health disorders among youths aged 15 to 24 is a significant public health concern. This systematic review aimed to explore global strategies for promoting mental well-being and addressing mental health challenges within this demographic, as defined by the World Health Organization. A comprehensive search of electronic scientific databases was conducted on November 1, 2023, yielding 43 studies with a total of 29,581 participants published between 2008 and 2023 that examined mental health interventions targeting youth.
View Article and Find Full Text PDFFood Sci Nutr
September 2025
Department of Biological Sciences, School of Science Hampton University Hampton Virginia USA.
Lemon balm (), a perennial herb belonging to the Lamiaceae family, is widely recognized for its medicinal properties and therapeutic benefits. This review offers a detailed exploration of the botanical features, phytochemical composition, and pharmacological uses of , highlighting key bioactive compounds such as phenolic acids (including rosmarinic and caffeic acids), flavonoids, essential oils (such as citral and citronellal), and triterpenoids (ursolic and oleanolic acids). Advanced extraction techniques, such as ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE), pressurized liquid extraction (PLE), supercritical fluid extraction (SFE), and matrix solid-phase dispersion (MSPD), have greatly improved the efficiency of extraction, the preservation of bioactivity, and the sustainability of acquiring these bioactive compounds.
View Article and Find Full Text PDFAlpha Psychiatry
August 2025
Center for Studies of Psychological Application, Guangdong Key Laboratory of Mental Health and Cognitive Science, and School of Psychology, South China Normal University, 510631 Guangzhou, Guangdong, China.
Background: Children's mental health is significantly influenced by family environments, where multiple risks often coexist, exert unequal impacts, and combine in different configurations that can result in diverse developmental outcomes. This study examines how different configurations of cumulative family risks influence mental health symptoms in Chinese children using a novel person-centered approach.
Materials And Methods: Data were collected through a large-scale, semester-based comprehensive survey of 34,041 children in Grades 4 to 6 in an economically underdeveloped county-level city in Guangdong, China, during November and December, 2022.