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Background: Corneal ulcers, often caused by eye trauma, are the main cause of corneal blindness. Knowledge of their symptom experiences and self-management is limited. The aim of this study was to describe the symptom experience and self-management of patients with corneal ulcers and to provide references for clinical medical staff to understand their impact on quality of life.
Methods: Between July and December 2022, semi-structured interviews were conducted with 20 patients with corneal ulcers who were hospitalised. Colaizzi's analysis was used to organise and analyse the interview data and this study followed the symptom management theory(SMT) model.
Results: The study comprised 10 male and 10 female patients with a mean age of 54.95 ± 8.41 years. Two major themes and six sub-themes were formed through the analysis of textual data: and the illustrated the distressing symptoms faced by patients and the subsequent effects on their daily lives, with ocular pain and blurred vision reported by nearly all patients. In an attempt to manage these symptoms, patients demonstrated a , which were derived from various sources, while also making adaptive changes to their daily lives.
Conclusion: This study revealed patients' experiences and strategies of symptom self-management, which may be a step towards providing a reference for evaluating the quality of life in patients with corneal ulcers.
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http://dx.doi.org/10.2147/PPA.S515296 | DOI Listing |
Cornea
September 2025
Icahn School of Medicine at Mount Sinai, Department of Ophthalmology, New York, NY.
Purpose: There is a lack of research on the extent to which non-Sjögren collagen vascular diseases affect the ocular surface. This study aims to understand the associations between collagen vascular diseases and dry eye and corneal ulcers.
Methods: This study analyzed a random 5% sample of national Medicare beneficiaries from 2011 to 2015 and included claims for those with collagen vascular diseases and either dry eye or corneal ulcers (n = 2,688,114).
Ophthalmology
September 2025
Francis I. Proctor Foundation, University of California San Francisco, USA; UCSF Department of Ophthalmology, University of California, San Francisco, USA; Byers Eye Institute, Stanford University, Palo Alto, USA. Electronic address:
Objective: To determine the effect of adjunctive rose-bengal photodynamic therapy (RB-PDT) in the treatment of fungal, Acanthamoeba, and smear/culture negative infectious keratitis.
Study Design: This international, randomized, double-masked, sham controlled clinical trial, randomizes patients with corneal ulcers in a 1:1 fashion to one of two treatment arms: 1) Topical antimicrobial plus sham RB-PDT or 2) Topical antimicrobial plus RB-PDT.
Main Outcome Measures: The primary outcome was best spectacle-corrected visual acuity (BSCVA) at 6 months.
Ocul Immunol Inflamm
September 2025
Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Purpose: To assess associations between hidradenitis suppurativa (HS) and inflammatory and infectious eye diseases.
Methods: We created a matched cohort of adults with and without a diagnosis of HS and calculated relative risk (RR) ratios for inflammatory and infectious eye diseases using the Global TriNetX Database. We also calculated RR ratios for infectious and inflammatory eye diseases in HS patients based on the use of biologic medications.
Vet Ophthalmol
August 2025
Animal Eye Care-Tokyo Animal Eye Clinic, Tokyo, Japan.
Objective: To describe the clinical manifestations and therapeutic outcomes of ocular infection caused by canine herpesvirus 1 (CHV-1), including both typical and atypical features.
Animal Studied: A client-owned 5-year-old castrated male French Bulldog presented with dendritic corneal ulcers, quantitative tear deficiency, and corneal hypoesthesia in the left eye.
Treatment And Progression: A diagnosis of CHV-1 ocular infection was made based on the characteristic presentation of dendritic corneal ulcers and confirmed by polymerase chain reaction (PCR) analysis of a conjunctival swab.
Exp Eye Res
August 2025
Department of Surgery and Radiology, Faculty of Veterinary Medicine Science, Islamic Azad University, Karaj, Iran.
Corneal ulcers pose a significant threat to vision and require timely, effective intervention to prevent permanent damage. This experimental study evaluated the therapeutic potential of combining crushed limbal tissue with either bovine amniotic membrane (AM) or a conjunctival flap to enhance corneal wound healing in a rabbit model. Twenty-five New Zealand white rabbits were randomly assigned to five groups: (G1) untreated control, (G2) AM alone, (G3) conjunctival flap alone, (G4) AM with crushed limbal tissue, and (G5) conjunctival flap with crushed limbal tissue.
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