98%
921
2 minutes
20
D.Don (Ericaceae) is a medicinal plant that occurs in the Swat District, Pakistan. Column chromatography was used to isolate cannabichromeorcinic acid (), cannabigerorcinic acid (), ursolic acid (), friedelin () and 2-phenylethyl 4-methoxybenzoate () from the methylene chloride extract of leaves that were collected from the Daral region in the Swat District, Pakistan. The structures of the isolated compounds were elucidated using nuclear magnetic resonance spectroscopy and mass spectrometry, and by comparison of the experimental data with those reported in the literature. The occurrence of cannabinoids () and (), triterpenoids () and (), and 2-phenylethyl 4-methoxybenzoate () in leaves, as reported in this study, may shed some light on this species' traditional medicinal uses.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/14786419.2025.2505601 | DOI Listing |
Mol Neurobiol
June 2025
Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai (Maharashtra), India.
Parkinson's disease is the second-most prevalent neurological disease globally, affecting about 8.5 million people. Ursolic acid (UA) is a widely distributed pentacyclic triterpenoid compound with various health benefits, including anti-inflammatory, antioxidant, antiviral and anti-tumor properties.
View Article and Find Full Text PDFPharmacol Res
June 2025
Department of Anesthesiology, Institute of Neurological Disease, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China; Department of Neurology and National Traditional Chinese Medicine Clinical Research Base, The Affiliated Traditional Chinese Medicine
Neuropathic pain (NPP) is a prevalent chronic condition characterized by spontaneous pain, hyperalgesia, allodynia, and sensory abnormalities, severely impacting patients' quality of life. Despite various guided treatments, their clinical efficacy remains limited, often accompanied by adverse reactions. Traditional Chinese medicine (TCM) offers unique advantages in disease treatment through its holistic approach (balancing the body as a unified system) and syndrome differentiation principle (personalized medicine).
View Article and Find Full Text PDFNat Prod Res
May 2025
Trait Diversity and Function Department, Royal Botanic Gardens Kew, Richmond, UK.
D.Don (Ericaceae) is a medicinal plant that occurs in the Swat District, Pakistan. Column chromatography was used to isolate cannabichromeorcinic acid (), cannabigerorcinic acid (), ursolic acid (), friedelin () and 2-phenylethyl 4-methoxybenzoate () from the methylene chloride extract of leaves that were collected from the Daral region in the Swat District, Pakistan.
View Article and Find Full Text PDFNat Commun
March 2025
Biochemical Engineering Group, Plant Biochemistry Section, Department of Plant and Environmental Sciences, University of Copenhagen, Thorvaldsensvej 40, 1871, Frederiksberg C, Denmark.
Natural products are widely used as pharmaceuticals, flavors, fragrances, and cosmetic ingredients. Synthesizing and evaluating analogs of natural products can considerably expand their applications. However, the chemical synthesis of analogs of natural products is severely hampered by their highly complex structures.
View Article and Find Full Text PDFMolecules
December 2024
Mibelle Group Biochemistry, Mibelle AG, 5033 Buchs, Switzerland.
L., specifically hemp, is a traditional herbaceous plant with industrial and medicinal uses. While much research has focused on cannabinoids and terpenes, the potential of hemp roots is less explored due to bioproduction challenges.
View Article and Find Full Text PDF