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Background: This research builds on the understanding that low self-acceptance is an important feature of adolescent depression, and that social comparison is a critical factor in self-concept formation during adolescence. However, there are gaps in our understanding of their interactive effects and the non-linear features between these factors in influencing adolescent depression.
Aim: The study attempts to test two main hypotheses: (1) increased levels of self-acceptance will correlate with reduced depressive symptoms and moderate the negative effects of social comparison on depression; and (2) the relationship between social comparison and depression will exhibit nonlinearity at different levels of self-acceptance.
Method: The study involved 243 adolescents undergoing psychiatric assessment, using dyadic polynomial regression analysis and response surface analysis. These methods were used to assess linearity or nonlinearity and interaction effects between self-acceptance, social comparison and depression.
Results: Significant findings included a strong negative correlation between self-acceptance and depression. Self-acceptance also showed a negative correlation with social comparison. Polynomial regression revealed a non-linear relationship between social comparison and depression, with moderate levels being beneficial but excessive levels being detrimental. The interaction effect suggested that high self-acceptance might buffer the negative effects of intense social comparison. Furthermore, response surface analysis revealed complex, non-linear interactions between these variables.
Conclusions: This study highlights the protective role of self-acceptance against depression and the complex, non-linear effects of social comparison. It highlights the importance of promoting self-acceptance and a balanced approach to social comparison in adolescent mental health interventions.
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http://dx.doi.org/10.1186/s12888-025-06873-6 | DOI Listing |
Int J Environ Health Res
September 2025
Department of Research, Unidad Médica de Alta Especialidad, Hospital de Especialidades, Instituto Mexicano del Seguro Social (IMSS), Veracruz, Mexico.
Little is known about the biomarkers of mortality in SARS-CoV-2-infected patients without a previous diagnosis of diabetes. Thus, this study aimed to assess the fibrinogen-to-platelet ratio (FPR) and compare its predictive value with the main biomarkers for COVID-19 mortality, such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), leukocyte glucose index (LGI), and lactate dehydrogenase (LDH)/lymphocyte ratio. This retrospective cohort study in a population of Mexico included 70 non-diabetic patients with COVID-19 from 1 May 2020 to 30 September 2020.
View Article and Find Full Text PDFJ Dermatolog Treat
December 2025
Pfizer Inc, New York, NY, USA.
Objectives: Vitiligo is an autoimmune disease resulting in skin depigmentation and individuals report substantial psychosocial burden. However, vitiligo-related quality of life impacts appear heterogeneous and may be influenced by social determinants of health. This cross-sectional survey aimed to describe characteristics and vitiligo-related quality of life impacts among adults in Brazil, China, India, and South Africa.
View Article and Find Full Text PDFObjectives: Vascular Cognitive Impairment (VCI) results from reduced cerebral blood flow, leading to cognitive dysfunction. This multicentre randomized controlled trial evaluated the clinical efficacy of acupuncture in improving cognitive function, daily living abilities, and quality of life in patients with Vascular Cognitive Impairment (VCI). In addition to standardized functional assessments, the authors also measured serum levels of BDNF, IL-6, and TNF-α as exploratory biomarkers of neuroplasticity and inflammation.
View Article and Find Full Text PDFDiabetes Res Clin Pract
September 2025
Université Paris Cité, ECEVE, UMR 1123, Inserm, F-75010 Paris, France; Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Service de santé publique, équipe REPERES, F-75019 Paris, France. Electronic address:
Aims: To study the association between socioeconomic status (SES) and hospital efficiency in Type 1 diabetes mellitus patients admitted for ketoacidosis or diabetic coma in mainland France, overall and in adults versus children.
Methods: An observational study was carried out using exhaustive national hospital discharge databases. It included all admissions discharged from 2013 to 2019.
Vaccine
September 2025
Department of Pharmacy, University of Rajshahi, Rajshahi 6205, Bangladesh.
Despite the therapeutic potential of the primary vaccine series, a lack of confidence in the COVID-19 booster vaccine poses a threat to public health and undermines its coverage at the national, regional, and global levels. This study aimed to understand COVID-19 booster vaccine confidence (CBVC) among Bangladeshi adults aged 18-49 and the potential predictors of CBVC. In line with STROBE guidelines, a face-to-face cross-sectional survey was conducted from June 15 to August 31, 2023 during the spread of the SARS-CoV-2 Omicron variant.
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