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The diverse natural landscapes and rich historical-cultural heritage have bestowed an abundant resource of ancient and notable trees (ANT) in Gansu Province. Currently, the green economy of ANT has become a pivotal avenue for the construction of ecological civilization in Gansu Province. Based on literature synthesis, we reviewed the current status of ANT resources in Gansu Province. The ANT resources in Gansu are mainly distributed in rural areas and remote mountainous regions. Human activities, pests, and diseases are the main threats to the survival of ANT in residential areas and their surroundings, while climate change, particularly drought, is the primary threat to ANT in remote mountainous areas. The research and management of ANT differ across regions: residential areas and their surrounding areas mainly focus on maintenance and rejuvenation techniques, while remote mountainous areas pay more attention to the development of the scientific value of ANT while neglecting the research on the protection of ANT. There are several challenges, including low accuracy and efficiency in age determination, poor feasibility of management, underdeveloped legal frameworks, and low public engagement. To overcome those challenges, we recommended to promote ANT protection from the following four aspects. 1) Prioritizing the development of tree-ring determination and tree-ring-diameter regression estimation methods. Establishing professional institutions or teams for the ANT protection to enhance the precision and efficiency of age determination. 2) Investigating the population characteristics and biological mechanisms of tree aging of ANT. 3) Deepening our understanding of tree growth patterns of ancient trees at different ages to propose practical conservation measures, and 4) Refining relevant laws and regulations, and increasing public participation.
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http://dx.doi.org/10.13287/j.1001-9332.202502.035 | DOI Listing |
Protein Pept Lett
September 2025
Department of Urology, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou730000, Gansu, China.
Introduction: Dysregulation of mevalonate metabolism is a hallmark of tumorigenesis and therapy resistance across malignancies, though its role in bladder cancer remains unclear. This study aimed to elucidate its impact on prognosis and cisplatin chemosensitivity in bladder cancer.
Methods: Transcriptomic data and clinical information of bladder cancer patients were obtained from The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO) databases.
Plant Cell Environ
September 2025
College of Horticulture, Gansu Agricultural University, Lanzhou, China.
This review discusses the research progress of regulating tree dwarfing in fruit tree rootstocks, including its definition, manifestation, mechanism and application of different rootstocks. Studies indicate that dwarfing rootstocks reduce vegetative growth while promoting reproductive growth. Compared with vigorous rootstocks, the contents of indole-3-acetic acid, cytokinin, and gibberellin in leaves is lower, while the content of abscisic acid is higher.
View Article and Find Full Text PDFJ Med Chem
September 2025
Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences & Research Unit of Peptide Science, Chinese Academy of Medical Sciences, 2019RU066, Lanzhou University, Lanzhou, Gansu 730000, P. R. China.
Hepatocellular carcinoma (HCC) remains a growing global health threat, necessitating the development of precise molecular probes for its prevention, early diagnosis, and treatment. Glypican-3 (GPC3) is highly expressed in various HCC subtypes and exhibits minimal expression in normal liver tissue, making it a promising biomarker for early-stage HCC diagnosis. Herein, we report a novel cyclic peptide molecular probe, 10P3Me, exhibiting high binding affinity for GPC3, with a of 93.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
Key Laboratory of Atomic and Molecular Physics & Functional Materials of Gansu Province, College of Physics and Electronic Engineering, Northwest Normal University, Lanzhou 730070, China.
Overcoming the persistent challenges of high operating temperatures and poor selectivity in metal oxide semiconductor (MOS) gas sensors, this work enhances defect sites in the sensing material through heterostructure construction and builds mesoporous architectures using MOF-derived carbon skeletons as templates. The synergistic effects of multiple mechanisms significantly improve gas-sensing performance, successfully fabricating a ZnO/PCS flexible room-temperature gas sensor with exceptional room-temperature DMF detection capabilities. The nitrogen-containing porous carbon skeletons (PCSs) template shows a stable mesoporous microstructure with large pore volume.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests, Hunan Agricultural University, Nongda Road 1, Furong District, Changsha City, Hunan Province 410128, PR China. Electronic address:
The genus Alternaria comprises a wide range of ubiquitous plant pathogens that affect various host plants. Certain mycoviruses can induce changes in the biological characteristics and virulence of host fungi, offering potential for biocontrol in managing fungal plant diseases. Here, we identified a mycovirus with a high degree of homology to Alternaria arborescens victorivirus 1 (AaVV1), which was previously reported from Alternaria arborescens, in the QRH strain of the heterologous host Alternaria gomphrenae.
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