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Background: Bowel symptoms are common in general practice and though most often benign they can also indicate colorectal cancer where a colonoscopy often is required to rule out malignant disease. Colon capsule endoscopy (CCE) is suggested as a more patient-friendly alternative to colonoscopy but its application in symptomatic patients in general practice needs further investigation.
Materials And Methods: We present a feasibility study of integrating initial triage for CCE into general practice. The technical success of CCE, patient acceptance, and the experiences of general practitioners (GPs) are assessed through qualitative interviews with participating GPs.
Results: We were able to recruit some general practices from the area of interest, but inclusion of patients was low. The participating GPs welcomed the concept of CCE as a more patient-friendly procedure and most patients invited by the GP accepted inclusion. Difficulties remembering the project in the diverse everyday of general practice, GP shortage and general time restraints were reported as barriers for patient recruitment by the GPs.
Conclusion: Before conducting large-scale implementation studies of CCE, our investigation highlighted critical barriers that need addressing: (1) Time Constraints and GP Shortages: The design of task divisions between sectors should carefully consider time limitations and the scarcity of GPs. (2) Low reinvestigation rates: Minimizing reinvestigation rates is crucial to reduce strain on both patients and healthcare systems.
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http://dx.doi.org/10.1186/s12875-025-02864-4 | DOI Listing |
JAMA Netw Open
September 2025
Harvard Medical School, Boston, Massachusetts.
Importance: Research in behavioral economics has demonstrated that people have irrational biases, which make them susceptible to decisional shortcuts, or heuristics. The extent to which physicians consciously might use nudges to exploit these heuristics and thereby influence their patients' decision-making is unclear. In addition, ethical questions about the conscious use of nudges in medicine persist, yet little is known about how physicians experience and perceive their use.
View Article and Find Full Text PDFEur Radiol Exp
September 2025
Department of Radio-diagnosis, Faculty of Human Medicine, Zagazig University, Zagazig, Egypt.
Background: Bone marrow (BM) lesion differentiation remains challenging, and quantitative magnetic resonance imaging (MRI) may enhance accuracy over conventional methods. We evaluated the diagnostic value and inter-reader reliability of Dixon-based signal drop (%drop) and fat fraction percentage (%fat) as adjuncts to existing protocols.
Materials And Methods: In this prospective two-center study, 172 patients with BM signal abnormalities underwent standardized 1.
Ned Tijdschr Geneeskd
September 2025
UMC Utrecht, afd. huisartsgeneeskunde, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Geneeskunde, Utrecht.
Objective: To investigate sex differences in the pharmacological treatment of hypertension in primary care.
Design: Cross-sectional study among 14,384 patients with hypertension from the Julius General Practitioners' Network, without cardiovascular disease or diabetes, treated with antihypertensive medications.
Methods: We compared men and women in the number and type of prescribed antihypertensives and their blood pressure.
Int J Surg
September 2025
Department of Interventional Ultrasound, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
Sonazoid, a combined blood pool and Kupffer-cell agent, can be specifically phagocytosed by Kupffer cells in the liver, allowing lesion detection and characterization of focal liver lesions (FLLs) at the post-vascular phase apart from the vascular phase which is similar to that of other second-generation US contrast agents. Sonazoid CEUS is currently approved for use in some Asian countries. With the increasing use of Sonazoid CEUS for FLLs in clinical practice, developing consensus or guidelines to help standardize its use is required.
View Article and Find Full Text PDFInt J Surg
September 2025
Digestive Endoscopy Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Background: Patients with T1 colorectal cancer (CRC) often show poor adherence to guideline-recommended treatment strategies after endoscopic resection. To address this challenge and improve clinical decision-making, this study aims to compare the accuracy of surgical management recommendations between large language models (LLMs) and clinicians.
Methods: This retrospective study enrolled 202 patients with T1 CRC who underwent endoscopic resection at three hospitals.