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Article Abstract
To search for and screen out effective antifungal lead compounds applicable to agriculture, a total of 21 tetrahydro--carboline derivatives were designed, synthesised, and evaluated for their antifungal activity. Based on biological studies, numerous compounds demonstrate notable antifungal properties . Specifically, compounds and showed higher efficacy against compared to carbendazim, with EC values of 16.43 mg/L and 12.72 mg/L, respectively. Additionally, compound exhibited exceptional antifungal activity against both and , achieving identical EC values of 12.71 mg/L for both pathogens. The results of this study will give reference for the additional design and structural optimisation of -carboalkaloids as possible agrochemical lead compounds for plant disease control.
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| http://dx.doi.org/10.1080/14786419.2025.2502853 | DOI Listing |
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