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To address the challenges of significant detail loss in Neural Radiance Fields (NeRF) under sparse-view input conditions, this paper proposes the DASNeRF framework. DASNeRF aims to generate high-detail novel views from a limited number of input viewpoints. To address the limitations of few-shot NeRF, including insufficient depth information and detail loss, DASNeRF introduces accurate depth priors and employs a depth constraint strategy combining relative depth ordering fidelity regularization and depth structural consistency regularization. These methods ensure reconstruction accuracy even with sparse input views. The depth priors provide high-quality depth data through a more accurate monocular depth estimation model, enhancing the reconstruction capability and stability of the model. The depth ordering fidelity regularization guides the network to learn relative relationships using local depth ranking priors, reducing blurring caused by inaccurate depth estimation. Depth structural consistency regularization maintains global depth consistency by enforcing continuity across neighboring depth pixels. These depth constraint strategies enhance DASNeRF's performance in complex scenes, making 3D reconstruction under sparse views more accurate and natural. In addition, we utilize a three-layer optimal sampling strategy, consisting of coarse sampling, optimized sampling, and fine sampling during the three-layer sampling process to better capture details in key regions. In the optimized sampling phase, the sampling point density in key regions is adaptively increased while reducing sampling in low-priority regions, enhancing detail capture accuracy. To alleviate overfitting, we proposed an MLP structure with per-layer input fusion. This design preserves the model's detail perception ability while effectively avoids overfitting. Specifically, each layer's input includes the output features from the previous layer and incorporates processed five-dimensional information, further enhancing fine detail reconstruction. Experimental results show that DASNeRF outperforms state-of-the-art methods on the LLFF and DTU dataset, achieving better performance in metrics such as PSNR, SSIM, and LPIPS. The reconstructed details and visual quality are significantly improved, demonstrating DASNeRF's potential in 3D reconstruction under sparse-view conditions.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068573 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0321878 | PLOS |
Clin Anat
September 2025
Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, South Korea.
Plantar melanomas present unique diagnostic and surgical challenges owing to substantial regional variations in skin thickness. Although the Breslow thickness remains the primary criterion for staging and surgical excision, its application on plantar melanoma is complicated by the inherent thickness of the glabrous plantar epidermis, which may lead to tumor depth overestimation. Accurate assessment of plantar skin thickness is essential for optimizing staging accuracy and refining surgical margins.
View Article and Find Full Text PDFMed Int (Lond)
August 2025
Department of Epidemiology, School of Public Health, Zhengzhou University, Zhengzhou, Henan 450001, P.R. China.
Punicalagin, a polyphenolic compound extracted from pomegranate peel, has received increasing attention in recent years due to its antibacterial and antiviral properties. Punicalagin is capable of inhibiting bacterial growth at sub-inhibitory concentrations by affecting cell membrane formation, disrupting membrane integrity, altering cell permeability, affecting efflux pumps, interfering with quorum sensing and influencing virulence factors. Additionally, punicalagin inhibits viruses by modulating enzyme activity, interacting with viral surface proteins, affecting gene expression, blocking viral attachment, disrupting virus receptor interaction and inhibiting viral replication.
View Article and Find Full Text PDFDiabetes Metab Syndr Obes
September 2025
Medical Research Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People's Republic of China.
Background: The methylation of and its influence on protein stability and degradation could play a crucial role in the pathogenesis of type 2 diabetes mellitus (T2DM), although the underlying molecular mechanisms are not yet fully understood. This study investigates the molecular and bioinformatic features of methylation in T2DM.
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J Healthc Sci Humanit
January 2024
Atlanta VA Medical Center, Atlanta, GA.
The 2019 novel coronavirus disease (COVID-19) has brought to the forefront racial disparities in health outcomes across the US, but there is limited formal analysis into factors associated with these disparities. In-depth examination of COVID-19 disparities has been challenging due to inconsistent case definition, isolation procedures, and incomplete racial and medical information. As of June 2020, over 14,000 (25%) confirmed COVID-19 cases in Georgia did not have racial information.
View Article and Find Full Text PDFJ Biomed Opt
September 2025
Leibniz University Hannover, Hannover Centre for Optical Technologies, Hannover, Germany.
Significance: Melanoma's rising incidence demands automatable high-throughput approaches for early detection such as total body scanners, integrated with computer-aided diagnosis. High-quality input data is necessary to improve diagnostic accuracy and reliability.
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